Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 6/20 | 0.33 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SLC8A1 | P32418 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7234327 | 0.89 | KMT2A (0.36) | CHRNB2CHRNA4MEN1KMT2ASLC8A1 | |
| SCHEMBL7232095 | 0.88 | CHRNA7 (0.34) | ALDH1A1SLC8A1 | |
| SCHEMBL7233323 | 0.87 | ESR1 (0.37) | ALDH1A1 | |
| SCHEMBL7224931 | 0.86 | F2 (0.37) | ALDH1A1CHRNB2CHRNA4KMT2A | |
| SCHEMBL7225149 | 0.86 | HTR4 (0.37) | ALDH1A1MAPTKDM4EGAAPOLB | |
| SCHEMBL7225066 | 0.86 | SLC6A4 (0.41) | CHRNB2CHRNA4KMT2AKDM4E | |
| SCHEMBL7229845 | 0.86 | SLC6A3 (0.42) | POLB | |
| SCHEMBL7225381 | 0.86 | HTR3E (0.37) | — | |
| SCHEMBL7232594 | 0.85 | HTT (0.40) | ALDH1A1HTTKDM4EGAA | |
| SCHEMBL7231419 | 0.84 | SCN9A (0.37) | MEN1KMT2AMAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |