Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 5/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.33 |
| ▸ | PLG | P00747 | 2/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223301 | 0.90 | MAPT (0.36) | KMT2AMMP2MMP7MMP9MMP13 | |
| SCHEMBL7232095 | 0.90 | CHRNA7 (0.34) | ST14ALDH1A1 | |
| SCHEMBL7233323 | 0.89 | ESR1 (0.37) | ALDH1A1 | |
| SCHEMBL7230406 | 0.88 | PARP14 (0.38) | F2PARP10PARP15PARP14CHRNB2 | |
| SCHEMBL7225066 | 0.88 | SLC6A4 (0.41) | KMT2ACHRNB2CHRNA4 | |
| SCHEMBL7229845 | 0.88 | SLC6A3 (0.42) | MMP13 | |
| SCHEMBL7225149 | 0.88 | HTR4 (0.37) | ALDH1A1 | |
| SCHEMBL7225381 | 0.87 | HTR3E (0.37) | MMP2MMP7MMP9MMP13 | |
| SCHEMBL7223387 | 0.86 | ALDH1A1 (0.35) | ALDH1A1KMT2ACHRNB2CHRNA4 | |
| SCHEMBL7231419 | 0.86 | SCN9A (0.37) | PARP10PARP15KMT2APARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |