SCHEMBL7227903

SCHEMBL7227903

COc1ccc(C(=O)NS(=O)(=O)c2ccccc2OC(F)(F)F)nc1Cl

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.46
CTSA P10619 2/20 0.43
ALPL P05186 4/20 0.42
KAT6A Q92794 1/20 0.42
KCNK3 O14649 1/20 0.42
KCNK9 Q9NPC2 1/20 0.42
SLC22A12 Q96S37 3/20 0.41
SLC40A1 Q9NP59 1/20 0.41
PTGER4 P35408 1/20 0.41
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
AXL P30530 1/20 0.38
IDH1 O75874 1/20 0.38
SCN9A Q15858 1/20 0.37
MRGPRX1 Q96LB2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7227102 0.88 FBP1 (0.43) FBP1ALPLKAT6AKCNK3KCNK9
SCHEMBL7235094 0.87 CTSA (0.42) FBP1CTSAALPLKAT6AKCNK3
SCHEMBL7227546 0.82 CTSA (0.46) CTSAKAT6ASLC40A1MEN1MAPT
SCHEMBL7235311 0.82 SLC40A1 (0.47) FBP1ALPLSLC22A12SLC40A1PTGER4
SCHEMBL7227108 0.82 FBP1 (0.49) FBP1ALPLSLC22A12SLC40A1PTGER4
SCHEMBL7227192 0.81 FBP1 (0.51) FBP1ALPLKCNK3KCNK9SLC22A12
SCHEMBL7235562 0.81 CTSA (0.44) CTSAKAT6AMEN1MAPTKMT2A
SCHEMBL7227358 0.79 ALPL (0.44) FBP1ALPLSLC22A12SLC40A1PTGER4
SCHEMBL7233807 0.76 CTSA (0.51) CTSAMEN1MAPTKMT2A
SCHEMBL30549039 0.75 ALPL (0.47) FBP1ALPLKAT6AKCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6610853-B1 N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide KUREHA KAGAKU KOGYO K.K. (JP) 2003-08-26 US disclosed
EP-1069112-A1 N-(PHENYLSULFONYL) PICOLINAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-01-17 EP disclosed