SCHEMBL7227358

SCHEMBL7227358

Cc1cc(Cl)nc(C(=O)NS(=O)(=O)c2ccccc2OC(F)(F)F)c1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALPL P05186 6/20 0.44
FBP1 P09467 1/20 0.44
SLC22A12 Q96S37 3/20 0.43
PTGER4 P35408 1/20 0.43
IDH1 O75874 1/20 0.41
SLC40A1 Q9NP59 1/20 0.41
MRGPRX1 Q96LB2 1/20 0.41
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
ATM Q13315 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ALKBH2 Q6NS38 2/20 0.39
ALKBH3 Q96Q83 2/20 0.39
FTO Q9C0B1 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.38
HSD17B13 Q7Z5P4 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7227192 0.88 FBP1 (0.51) ALPLFBP1SLC22A12PTGER4IDH1
SCHEMBL7235311 0.84 SLC40A1 (0.47) ALPLFBP1SLC22A12PTGER4IDH1
SCHEMBL7226318 0.79 CA1 (0.45) SLC40A1KDM4EMAPTALKBH2ALKBH3
SCHEMBL7227903 0.79 FBP1 (0.46) ALPLFBP1SLC22A12PTGER4IDH1
SCHEMBL7234807 0.78 ALDH1A1 (0.42) KDM4EALKBH2ALKBH3
SCHEMBL7233988 0.77 SLC22A12 (0.47) ALPLFBP1SLC22A12PTGER4IDH1
SCHEMBL22427667 0.77 FBP1 (0.45) ALPLFBP1SLC22A12PTGER4IDH1
SCHEMBL7227102 0.75 FBP1 (0.43) ALPLFBP1SLC22A12PTGER4SLC40A1
SCHEMBL7227108 0.75 FBP1 (0.49) ALPLFBP1SLC22A12PTGER4SLC40A1
SCHEMBL30549039 0.75 ALPL (0.47) ALPLFBP1SLC22A12PTGER4IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6610853-B1 N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide KUREHA KAGAKU KOGYO K.K. (JP) 2003-08-26 US disclosed
EP-1069112-A1 N-(PHENYLSULFONYL) PICOLINAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-01-17 EP disclosed