Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2066405 | 1.00 | ADRA2C (0.53) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL13971006 | 1.00 | ADRA2C (0.53) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL4074447 | 1.00 | ADRA2C (0.53) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL23980139 | 0.78 | LMNA (0.50) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL2736639 | 0.78 | LMNA (0.50) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL27257662 | 0.78 | LMNA (0.50) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL12418041 | 0.78 | KDM4E (0.59) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL5172179 | 0.78 | KDM4E (0.59) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL837417 | 0.78 | KDM4E (0.59) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL4272229 | 0.78 | KDM4E (0.59) | ADRA2CKDM4EADRA2ALMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433897-B1 | Process for preparing an optically active cyclobutane nucleoside | SQUIBB & SONS INC (US) | 1997-10-01 | — | — | EP | claimed |
| US-5064961-A | PROCESS FOR PREPARING AN OPTICALLY ACTIVE CYCLOBUTANE NUCLEOSIDE | E. R. SQUIBB & SONS, INC. (US) | 1991-11-12 | — | — | US | claimed |
| EP-0433897-A2 | Process for preparing an optically active cyclobutane nucleoside | E.R. SQUIBB & SONS, INC. (US) | 1991-06-26 | — | — | EP | claimed |
| US-20240124408-A1 | Substituted Cyclohexanecarboxamides, Their Preparation and Their Therapeutic Application | SANOFI (FR) | 2024-04-18 | — | — | US | disclosed |
| US-20120048295-A1 | CLEANING FORMULATION FOR REMOVING RESIDUES ON SURFACES | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2012-03-01 | — | — | US | disclosed |
| WO-2010104816-A1 | CLEANING FORMULATION FOR REMOVING RESIDUES ON SURFACES | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2010-09-16 | — | — | WO | disclosed |
| US-7306884-B2 | Dye-containing curable composition, color filter prepared using the same, and process of preparing color filter | FUJIFILM CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| US-7306884-B2 | Dye-containing curable composition, color filter prepared using the same, and process of preparing color filter | FUJIFILM CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| US-20070072096-A1 | Negative curable dye-containing composition, color filter, and method of manufacturing the same | FUJI PHOTO FILM CO., LTD. | 2007-03-29 | — | — | US | disclosed |
| US-7078406-B2 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, L.L.C. (US) | 2006-07-18 | — | — | US | disclosed |
| US-20040248851-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | Life Technologies Corporation | 2004-12-09 | — | — | US | disclosed |
| US-5198583-A | Optically active cyclobutane nucleoside and intermediates, therefor | E. R. SQUIBB & SONS, INC. (US) | 1993-03-30 | — | — | US | disclosed |
| US-5064961-A | PROCESS FOR PREPARING AN OPTICALLY ACTIVE CYCLOBUTANE NUCLEOSIDE | E. R. SQUIBB & SONS, INC. (US) | 1991-11-12 | — | — | US | disclosed |
| EP-0433897-A2 | Process for preparing an optically active cyclobutane nucleoside | E.R. SQUIBB & SONS, INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| US-4256911-A | TRIFLUOROMETHYL-CARBOXY ESTERS | HOFFMANN-LA ROCHE INC. (US) | 1981-03-17 | — | — | US | disclosed |
| US-4237276-A | CARDIOVASCULAR AGENTS, INDUCTION OF LABOR, TERMINATION OF PREGNANCY | HOFFMANN-LA ROCHE INC. (US) | 1980-12-02 | — | — | US | disclosed |
| US-4211724-A | ENANTIOMORPHS, INTERMEDIATE AMIDES WITH ASSYMETRIC CARBON ATOM | HOFFMAN-LA ROCHE INC. (US) | 1980-07-08 | — | — | US | disclosed |
| US-4190587-A | PROSTAGLANDINS | HOFFMANN-LA ROCHE INC. (US) | 1980-02-26 | — | — | US | disclosed |
| US-4187381-A | CARDIOVASCULAR AGENTS; OXYTOCICS | HOFFMANN-LA ROCHE INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-4112225-A | 16-CF3 prostaglandins | HOFFMAN-LA ROCHE INC. (US) | 1978-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248851-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | DHFR, FPR1, CYP1A1 | ADRA2C 2623/4885KDM4E 1438/4885ADRA2A 2908/4885 |
| US-20240124408-A1 | Substituted Cyclohexanecarboxamides, Their Preparation and Their Therapeutic Application | TRPM8, TAS2R8, TRPM7 | ADRA2C 465/4885KDM4E 2867/4885ADRA2A 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.