Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7234830 | 0.85 | RAB9A (0.42) | NPC1RAB9AHTTSMN1; SMN2MEN1 | |
| SCHEMBL7225840 | 0.84 | RAB9A (0.41) | NPC1RAB9AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7072612 | 0.84 | RAB9A (0.49) | NPC1RAB9AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7226764 | 0.84 | RAB9A (0.53) | NPC1RAB9AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7231145 | 0.84 | SLC9A1 (0.44) | NPC1RAB9AHTTSMN1; SMN2LMNA | |
| SCHEMBL7233102 | 0.84 | ALDH1A1 (0.49) | NPC1RAB9AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7226523 | 0.83 | SMN1; SMN2 (0.42) | NPC1RAB9AALDH1A1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7070829 | 0.83 | RAB9A (0.48) | NPC1RAB9AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7231428 | 0.83 | FAAH (0.46) | KDM1ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7232158 | 0.82 | ALDH1A1 (0.50) | NPC1RAB9AALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |