Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.36 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15643677 | 1.00 | MAPT (0.40) | MAPTL3MBTL1RAB9ASENP7CASP3 | |
| SCHEMBL530698 | 0.84 | KCNN4 (0.38) | MAPTL3MBTL1RAB9ASENP7CASP3 | |
| SCHEMBL155459 | 0.80 | MAPT (0.46) | MAPTL3MBTL1RAB9ASENP7CASP3 | |
| SCHEMBL27935083 | 0.80 | MAPT (0.49) | MAPTL3MBTL1RAB9ASENP7CASP3 | |
| SCHEMBL113257 | 0.80 | MAPT (0.46) | MAPTL3MBTL1RAB9ASENP7CASP3 | |
| SCHEMBL29763577 | 0.79 | MAPT (0.42) | MAPTL3MBTL1KMT2AMEN1MAPK1 | |
| SCHEMBL10415826 | 0.73 | ALDH1A1 (0.50) | MAPTL3MBTL1RAB9ASENP7CASP3 | |
| SCHEMBL28556998 | 0.73 | CYP2D6 (0.51) | MAPTL3MBTL1RAB9ASENP7CASP3 | |
| SCHEMBL7185639 | 0.73 | ALDH1A1 (0.43) | MAPTMYCKMT2ATDP1SMN1; SMN2 | |
| SCHEMBL4287836 | 0.73 | GABRA1 (0.37) | MAPTRAB9AMYCKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024064769-A1 | INDUCTION OF STEM-LIKE ACTIVATED T CELLS | PHIO PHARMACEUTICALS CORP. (US) | 2024-03-28 | — | — | WO | disclosed |
| US-20230416283-A1 | CROSSLINKING COMONOMERS FOR HIGH PERFORMANCE DEGRADABLE THERMOSETS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-12-28 | — | — | US | disclosed |
| EP-3775203-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | Wave Life Sciences Ltd. (SG) | 2021-02-17 | — | — | EP | disclosed |
| EP-3645600-A1 | CORE-TO-SURFACE POLYMERIZATION FOR THE SYNTHESIS OF STAR POLYMERS AND USES THEREOF | Massachusetts Institute of Technology (US) | 2020-05-06 | — | — | EP | disclosed |
| US-10633407-B2 | 14-membered ketolides and methods of their preparation and use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-04-28 | — | — | US | disclosed |
| WO-2019200185-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2019-10-17 | — | — | WO | disclosed |
| EP-3544971-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2019-10-02 | — | — | EP | disclosed |
| WO-2019032961-A1 | TRIOXACARCIN-ANTIBODY CONJUGATES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-02-14 | — | — | WO | disclosed |
| WO-2019006425-A1 | BRUSH-ARM STAR POLYMER IMAGING AGENTS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-03 | — | — | WO | disclosed |
| WO-2019006422-A1 | CORE-TO-SURFACE POLYMERIZATION FOR THE SYNTHESIS OF STAR POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-03 | — | — | WO | disclosed |
| US-9080171-B2 | Reduced size self-delivering RNAi compounds | RXi Parmaceuticals Corporation (US) | 2015-07-14 | — | — | US | disclosed |
| EP-2791128-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | Olema Pharmaceuticals, Inc. (US) | 2014-10-22 | — | — | EP | disclosed |
| WO-2014160441-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140113950-A1 | INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS | RXI PHARMACEUTICALS CORPORATION (US) | 2014-04-24 | — | — | US | disclosed |
| WO-2013090921-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2013-06-20 | — | — | WO | disclosed |
| WO-2012027555-A2 | GLYCATED CD59 PEPTIDES, THEIR PREPARATION, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-03-01 | — | — | WO | disclosed |
| EP-2348845-A1 | ANSAMYCIN HYDROQUINONE COMPOSITIONS | Infinity Pharmaceuticals, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-2337809-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | Novomer, Inc. (US) | 2011-06-29 | — | — | EP | disclosed |
| WO-2010045442-A1 | ANSAMYCIN HYDROQUINONE COMPOSITIONS | INFINITY DISCOVERY, INC. (US) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010028362-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416283-A1 | CROSSLINKING COMONOMERS FOR HIGH PERFORMANCE DEGRADABLE THERMOSETS | PGD, CDCA2, MCM2 | MAPT 684/4885L3MBTL1 3620/4885RAB9A 3389/4885 |
| US-10633407-B2 | 14-membered ketolides and methods of their preparation and use | CYP51A1, HSD17B7, CYP11B1 | MAPT 2547/4885L3MBTL1 3210/4885RAB9A 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.