Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL723408

O.O=C([O-])C(F)(F)F.O=C([O-])C(F)(F)F.[Zn+2]

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.36
CA2 P00918 1/20 0.35
CASP1 P29466 1/20 0.32
CA1 P00915 1/20 0.31
FAHD1 Q6P587 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL28696706 1.00 CA4 (0.36) CA4CA2CASP1CA1FAHD1
Trifluoroacetic Acid SCHEMBL379347 0.96 CA4 (0.38) CA4CA2CASP1CA1FAHD1
Trifluoroacetic Acid SCHEMBL31606587 0.96 CA4 (0.38) CA4CA2CASP1CA1FAHD1
Trifluoroacetic Acid SCHEMBL31220276 0.92 CA4 (0.36) CA4CA2CASP1CA1FAHD1
Trifluoroacetic Acid SCHEMBL31220183 0.92 CA4 (0.36) CA4CA2CASP1CA1FAHD1
Trifluoroacetic Acid SCHEMBL31220198 0.92 CA4 (0.36) CA4CA2CASP1CA1FAHD1
Trifluoroacetic Acid SCHEMBL29776711 0.92 CA4 (0.36) CA4CA2CASP1CA1FAHD1
Trifluoroacetic Acid SCHEMBL585599 0.92 CA4 (0.36) CA4CA2CASP1CA1FAHD1
Trifluoroacetic Acid SCHEMBL225730 0.92 CA4 (0.36) CA4CA2CASP1CA1FAHD1
Trifluoroacetic Acid SCHEMBL29003430 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023989-A1 SALT ADDITIVES FOR SECONDARY SULFUR BATTERIES CONAMIX INC. 2023-01-26 US claimed
EP-4094321-A1 SALT ADDITIVES FOR SECONDARY SULFUR BATTERIES Conamix Inc. (US) 2022-11-30 EP claimed
WO-2016150823-A1 METHOD USING ZINC CATALYST FOR PRODUCING CARBAMATE-FUNCTIONAL MATERIALS BASF COATINGS GMBH (DE) 2016-09-29 WO claimed
US-9353433-B2 Method of fabricating liquid for oxide thin film INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2016-05-31 US claimed
US-9123818-B2 Compositions for solution process, electronic devices fabricated using the same, and fabrication methods thereof INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2015-09-01 US claimed
US-8765028-B2 Composition for oxide thin film, method of preparing the composition, method of forming the oxide thin film, and electronic device using the composition INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2014-07-01 US claimed
US-20140000480-A1 METHOD OF FABRICATING LIQUID FOR OXIDE THIN FILM INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2014-01-02 US claimed
US-8523996-B2 Method of fabricating liquid for oxide thin film INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2013-09-03 US claimed
US-20120080678-A1 COMPOSITIONS FOR SOLUTION PROCESS, ELECTRONIC DEVICES FABRICATED USING THE SAME, AND FABRICATION METHODS THEREOF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2012-04-05 US claimed
US-20120049181-A1 COMPOSITION FOR OXIDE THIN FILM, METHOD OF PREPARING THE COMPOSITION, METHOD OF FORMING THE OXIDE THIN FILM, AND ELECTRONIC DEVICE USING THE COMPOSITION INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2012-03-01 US claimed
US-20100251936-A1 METHOD OF FABRICATING LIQUID FOR OXIDE THIN FILM INDUSTRY-ACADEMIC COOPERATION FOUNDATION , (KR) 2010-10-07 US claimed
WO-2025203024-A1 PROCESS FOR PREPARING 5-FLUORO-4-IMINO-3-METHYL-1-(TOLUENE-4-SULFONYL)-3,4-DIHYDRO-1H-PYRIMIDIN-2-ONE ADAMA MAKHTESHIM LTD. (IL) 2025-10-02 WO disclosed
CN-118702568-A Application of tetranuclear metal cluster catalyst in degradation and shrinkage cluster plastic 南京工业大学 2024-09-27 CN disclosed
EP-4169969-A1 POLYCARBAMATE Dow Global Technologies Llc (US) 2023-04-26 EP disclosed
US-20230023989-A1 SALT ADDITIVES FOR SECONDARY SULFUR BATTERIES CONAMIX INC. 2023-01-26 US disclosed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US disclosed
US-20050272839-A1 Compression-granulated flame retardant composition CLARIANT GMBH 2005-12-08 US disclosed
US-20050222309-A1 Phosphorus-containing flame retardant formulation for cellulose-containing moldings CLARIANT GMBH 2005-10-06 US disclosed
US-20050143503-A1 Phosphorus-containing flame retardant agglomerates CLARIANT GMBH 2005-06-30 US disclosed
US-20050137418-A1 Process for preparation of dialkylphosphinic salts CLARIANT GMBH 2005-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 CA4 7/4885CA2 32/4885CASP1 2603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.