SCHEMBL7236182

SCHEMBL7236182

Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3cccc(OCC(=O)O)c3)c(C#N)cc2F)c1=O

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 15/20 0.51
BCAT2 O15382 14/20 0.51
LMNA P02545 1/20 0.35
FFAR1 O14842 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6263807 0.88 BCAT1 (0.50) BCAT1BCAT2
SCHEMBL27047526 0.88 BCAT1 (0.52) BCAT1BCAT2
SCHEMBL7233936 0.87 LMNA (0.37) BCAT1BCAT2LMNAFFAR1PTGDR2
SCHEMBL6248581 0.87 BCAT1 (0.54) BCAT1BCAT2
SCHEMBL6244770 0.86 BCAT1 (0.53) BCAT1BCAT2
SCHEMBL27047543 0.85 BCAT1 (0.45) BCAT1BCAT2FFAR1PTGDR2
SCHEMBL27047576 0.85 PTGDR2 (0.43) BCAT1BCAT2PTGDR2
SCHEMBL7227999 0.84 BCAT1 (0.47) BCAT1BCAT2
SCHEMBL27047561 0.84 BCAT2 (0.42) BCAT1BCAT2PTGDR2
SCHEMBL27044949 0.82 BCAT1 (0.50) BCAT1BCAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6667413-B2 Aniline derivatives; herbicides; nonphytotoxic SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-23 US disclosed
US-20030130124-A1 Herbicides SUMITOMO CHEMICAL COMPANY, LIMITED 2003-07-10 US disclosed
US-6451740-B2 HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-17 US disclosed
US-20020013466-A1 Uracil compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-31 US disclosed
EP-1106607-A2 Uracil compounds and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030130124-A1 Herbicides CBR3, CBR1, MT-CO1 BCAT1 492/4885BCAT2 650/4885LMNA 2498/4885
US-20020013466-A1 Uracil compounds and use thereof UNG, MRM1, OGG1 BCAT1 450/4885BCAT2 648/4885LMNA 2074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.