Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397776 | 0.78 | MAPT (0.50) | ADRA2AADRA2BADRA2CNISCHMTOR | |
| SCHEMBL14886220 | 0.78 | CSNK1A1 (0.53) | ADRA2AADRA2BADRA2CNISCHMTOR | |
| SCHEMBL8342759 | 0.77 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CNISCHMTOR | |
| SCHEMBL3053174 | 0.77 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CNISCHMTOR | |
| SCHEMBL27767007 | 0.76 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CNISCHMTOR | |
| SCHEMBL9682527 | 0.75 | NISCH (0.54) | ADRA2AADRA2BADRA2CNISCHMTOR | |
| SCHEMBL5914840 | 0.70 | NISCH (0.41) | ADRA2AADRA2BADRA2CNISCHMTOR | |
| SCHEMBL9804680 | 0.70 | KMT2A (0.46) | ADRA2AADRA2BADRA2CNISCHMTOR | |
| SCHEMBL8592483 | 0.70 | WDR5 (0.45) | ADRA2AADRA2BADRA2CNISCHMTOR | |
| SCHEMBL51007 | 0.69 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CNISCHMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055255-A1 | Synthesis of substituted imidazoles | MARCANTONIO KAREN (US) | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055255-A1 | Synthesis of substituted imidazoles | KARS1, TKT, AADAC | ADRA2A 1417/4885ADRA2B 3007/4885ADRA2C 1695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.