SCHEMBL723922

SCHEMBL723922

OCC(O)C(O)CCC(CO)(CO)CO

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 2/20 0.30
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E968 SCHEMBL2138801 0.82 LMNA (0.47) LMNAL3MBTL1TDP1ALDH1A1TSHR
E968 SCHEMBL5923897 0.82 LMNA (0.47) LMNAL3MBTL1TDP1ALDH1A1TSHR
SCHEMBL30491743 0.78 LMNA (0.38) LMNAL3MBTL1TDP1
SCHEMBL11126683 0.77 TRPV1 (0.31)
SCHEMBL11890974 0.76 RIPK1 (0.39) LMNAL3MBTL1TDP1
SCHEMBL6450343 0.76 TDP1 (0.32) TDP1ALDH1A1
SCHEMBL17516304 0.76 RIPK1 (0.39) LMNAL3MBTL1TDP1
SCHEMBL5907395 0.74 LMNA (0.40) LMNAL3MBTL1TDP1ALDH1A1TSHR
Sorbitol SCHEMBL9446139 0.74 LMNA (0.65) LMNAL3MBTL1TDP1ALDH1A1TSHR
SCHEMBL1904081 0.74 THRB (0.50) LMNAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1490485-B1 GRANULES WITH FILAMENTOUS COATINGS NOVOZYMES AS (DK) 2015-03-04 EP claimed
US-11292873-B2 Etheramines prepared from a mixture of two or more multifunctional alcohol initiators, and their use as curatives or intermediates for polymer synthesis HUNTSMAN PETROCHEMICAL LLC (US) 2022-04-05 US disclosed
CN-114163628-A Etheramines and their use as curing agents or intermediates for polymer synthesis 亨斯迈石油化学有限责任公司 2022-03-11 CN disclosed
US-11015015-B2 Co-preparation of polyetheramines and alklyene amines HUNTSMAN PETROCHEMICAL LLC (US) 2021-05-25 US disclosed
US-20200062890-A1 ETHERAMINES PREPARED FROM A MIXTURE OF TWO OR MORE MULTIFUNCTIONAL ALCOHOL INITIATORS, AND THEIR USE AS CURATIVES OR INTERMEDIATES FOR POLYMER SYNTHESIS HUNTSMAN PETROCHEMICAL LLC 2020-02-27 US disclosed
CN-105637002-B Etheramines with enhanced thermal stability and their use as curing agents or intermediates in polymer synthesis 亨斯迈石油化学有限责任公司 2019-08-16 CN disclosed
EP-3058007-B1 ETHERAMINES WITH ENHANCED THERMAL STABILITY AND THEIR USE AS CURATIVES OR INTERMEDIATES FOR POLYMER SYNTHESIS HUNTSMAN PETROCHEMICAL LLC (US) 2018-12-12 EP disclosed
EP-3402776-A1 CO-PREPARATION OF POLYETHERAMINES AND ALKYLENE AMINES Huntsman Petrochemical LLC (US) 2018-11-21 EP disclosed
US-20180312624-A1 CO-PREPARATION OF POLYETHERAMINES AND ALKLYENE AMINES HUNTSMAN PETROCHEMICAL LLC 2018-11-01 US disclosed
US-9822215-B2 Etheramines with enhanced thermal stability and their use as curatives or intermediates for polymer synthesis HUNTSMAN PETROCHEMICAL LLC (US) 2017-11-21 US disclosed
US-20160257777-A1 Etheramines with Enhanced Thermal Stability and their Use as Curatives or Intermediates for Polymer Synthesis HUNTSMAN PETROCHEMICAL LLC 2016-09-08 US disclosed
US-20160257778-A1 Etheramines and their Use as Curatives or Intermediates for Polymer Synthesis HUNTSMAN PETROCHEMICAL LLC 2016-09-08 US disclosed
EP-3058007-A1 ETHERAMINES WITH ENHANCED THERMAL STABILITY AND THEIR USE AS CURATIVES OR INTERMEDIATES FOR POLYMER SYNTHESIS Huntsman Petrochemical LLC (US) 2016-08-24 EP disclosed
CN-105705015-A Etheramines and their use as curing agents or intermediates for polymer synthesis 亨斯迈石油化学有限责任公司 2016-06-22 CN disclosed
CN-105637002-A Etheramines with enhanced thermal stability and their use as curing agents or intermediates in polymer synthesis HUNTSMAN PETROCHEMICAL LLC 2016-06-01 CN disclosed
WO-2015069531-A1 ETHERAMINES AND THEIR USE AS CURATIVES OR INTERMEDIATES FOR POLYMER SYNTHESIS HUNTSMAN PETROCHEMICAL LLC (US) 2015-05-14 WO disclosed
WO-2015058032-A1 ETHERAMINES WITH ENHANCED THERMAL STABILITY AND THEIR USE AS CURATIVES OR INTERMEDIATES FOR POLYMER SYNTHESIS HUNTSMAN PETROCHEMICAL LLC (US) 2015-04-23 WO disclosed
US-5861471-A FOR LOW TEMPERATURE EXTRUSION AND WORKABILITY, STABILITY, HEAT RESISTANCE, BLOOD COMPATIBILITY; FOR TUBES, MEMBRANES, MEDICAL EQUIPMENT BAYER AC (DE) 1999-01-19 US disclosed
EP-0503864-A2 Coating compositions CIBA-GEIGY AG (CH) 1992-09-16 EP disclosed
EP-0055975-A1 Stable, non aqueous textile auxiliary and its use in the oxidative desizing of cellulose containing fibrous materials CIBA-GEIGY AG (CH) 1982-07-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160257778-A1 Etheramines and their Use as Curatives or Intermediates for Polymer Synthesis PNMT, ALKBH2, HCCS LMNA 87/4885L3MBTL1 1921/4885TDP1 1003/4885
US-20200062890-A1 ETHERAMINES PREPARED FROM A MIXTURE OF TWO OR MORE MULTIFUNCTIONAL ALCOHOL INITIATORS, AND THEIR USE AS CURATIVES OR INTERMEDIATES FOR POLYMER SYNTHESIS PNMT, ALKBH2, ADH1A LMNA 77/4885L3MBTL1 2222/4885TDP1 981/4885
US-11015015-B2 Co-preparation of polyetheramines and alklyene amines PUF60, PNMT, ALKBH3 LMNA 321/4885L3MBTL1 2124/4885TDP1 476/4885
US-11292873-B2 Etheramines prepared from a mixture of two or more multifunctional alcohol initiators, and their use as curatives or intermediates for polymer synthesis PNMT, ALKBH2, ADH1A LMNA 77/4885L3MBTL1 2222/4885TDP1 981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.