Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7246414 | 0.90 | — | — | |
| SCHEMBL2659911 | 0.87 | KCNN4 (0.32) | KCNN4 | |
| SCHEMBL2657966 | 0.83 | KDM4E (0.32) | KCNN4 | |
| SCHEMBL2658688 | 0.83 | ADRA2A (0.32) | KCNN4 | |
| SCHEMBL2659044 | 0.73 | GSK3A (0.34) | — | |
| SCHEMBL2659511 | 0.70 | GABRG2 (0.42) | — | |
| SCHEMBL7239591 | 0.70 | GABRA1 (0.36) | KCNN4 | |
| SCHEMBL7241252 | 0.70 | KCNN4 (0.41) | KCNN4 | |
| SCHEMBL2659865 | 0.66 | NPSR1 (0.33) | — | |
| SCHEMBL2659828 | 0.63 | ADORA2A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073717-A1 | Triazolo-pyridine derivatives as ligands for GABA receptors | MERCK & CO., INC. | 2003-04-17 | — | — | US | disclosed |
| US-6479506-B1 | USEFUL IN THE THERAPY OF DELETERIOUS MENTAL STATES SUCH AS ANXIETY | MERCK SHARP & DOHME LTD. (GB) | 2002-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073717-A1 | Triazolo-pyridine derivatives as ligands for GABA receptors | GABRA3, GABRA4, GABRA5 | KCNN4 347/4885CRHR1 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.