Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.31 |
| ▸ | HTR1A | P08908 | 3/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940682 | 0.92 | PPARD (0.35) | PPARDMEN1KMT2APKMADRA1A | |
| SCHEMBL6152772 | 0.89 | TBXA2R (0.36) | MEN1KMT2AADRA1AHTR1ATBXA2R | |
| SCHEMBL7247859 | 0.84 | HTR1A (0.35) | ADRA1AHTR1ATBXA2RSLC6A3ADRA2A | |
| SCHEMBL6152961 | 0.83 | HTR1A (0.30) | ADRA1AHTR1ATBXA2RSLC6A3ADRA2A | |
| SCHEMBL6942911 | 0.80 | ABCB11 (0.33) | MEN1KMT2AADRA1AHTR1ATBXA2R | |
| SCHEMBL6940628 | 0.80 | CYP2C9 (0.36) | MEN1KMT2AADRA1AHTR1ATBXA2R | |
| SCHEMBL6945502 | 0.80 | HSD17B10 (0.36) | MEN1KMT2AADRA1AHTR1ATBXA2R | |
| SCHEMBL6154618 | 0.80 | KDM4E (0.36) | MEN1KMT2AADRA1AHTR1ATBXA2R | |
| SCHEMBL7843083 | 0.79 | ALDH1A1 (0.41) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL6153193 | 0.79 | LMNA (0.36) | MEN1KMT2AADRA1AHTR1ATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653313-B2 | For treatment and prevention of inflammation, asthma, allergic rhinitis, pain and other disorders | WARNER-LAMBERT COMPANY LLC | 2003-11-25 | — | — | US | disclosed |
| US-20020161006-A1 | 1,4-dihydropyridine compounds as bradykinin antagonists | KAWAMURA MITSUHIRO (US) | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161006-A1 | 1,4-dihydropyridine compounds as bradykinin antagonists | BDKRB1, BDKRB2, HRH4 | PPARD 4092/4885MEN1 2435/4885KMT2A 1890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.