SCHEMBL724520

SCHEMBL724520

CCCCCC1=CCCCC1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
ALOX15 P16050 2/20 0.47
PKM P14618 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
RAB9A P51151 1/20 0.41
USP2 O75604 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
LMNA P02545 1/20 0.39
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9213508 0.98 ALDH1A1 (0.46) ALDH1A1ALOX15PKMSMN1; SMN2RAB9A
SCHEMBL11236829 0.98 ALDH1A1 (0.46) ALDH1A1ALOX15PKMSMN1; SMN2RAB9A
SCHEMBL6839659 0.98 ALDH1A1 (0.46) ALDH1A1ALOX15PKMSMN1; SMN2RAB9A
SCHEMBL61669 0.98 ALDH1A1 (0.46) ALDH1A1ALOX15PKMSMN1; SMN2RAB9A
SCHEMBL7459531 0.98 ALDH1A1 (0.46) ALDH1A1ALOX15PKMSMN1; SMN2RAB9A
SCHEMBL60610 0.98 ALDH1A1 (0.46) ALDH1A1ALOX15PKMSMN1; SMN2RAB9A
SCHEMBL11236833 0.98 ALDH1A1 (0.46) ALDH1A1ALOX15PKMSMN1; SMN2RAB9A
SCHEMBL28861193 0.98 ALDH1A1 (0.46) ALDH1A1ALOX15PKMSMN1; SMN2RAB9A
SCHEMBL11236830 0.98 ALDH1A1 (0.46) ALDH1A1ALOX15PKMSMN1; SMN2RAB9A
SCHEMBL25337874 0.96 ALDH1A1 (0.45) ALDH1A1ALOX15PKMSMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2398831-B1 AQUEOUS POLYMER DISPERSION MADE OF A VINYLAROMATIC COMPOUND, CONJUGATED ALIPHATIC DIENE, AND ETHYLENICALLY UNSATURATED ACID BASF SE (DE) 2013-05-29 EP claimed
US-20110281130-A1 AQUEOUS POLYMER DISPERSION OBTAINED FROM A VINYLAROMATIC COMPOUND, CONJUGATED ALIPHATIC DIENE AND ETHYLENICALLY UNSATURATED ACID BASF SE (DE) 2011-11-17 US claimed
US-12018001-B2 Pyrimidine cyclohexenyl glucocorticoid receptor modulators CORCEPT THERAPEUTICS INCORPORATED (US) 2024-06-25 US disclosed
EP-3802499-B1 PYRIMIDINE CYCLOHEXENYL GLUCOCORTICOID RECEPTOR MODULATORS CORCEPT THERAPEUTICS INC (US) 2024-04-10 EP disclosed
WO-2024068674-A1 NUCLEIC ACID COMPLEXES AND USES THEREOF BioNTech SE (DE) 2024-04-04 WO disclosed
US-11945808-B2 Substituted cyclohexyl compounds as NOP inhibitors DART NEUROSCIENCE, LLC (US) 2024-04-02 US disclosed
US-11932601-B2 Immunoregulatory agents FLEXUS BIOSCIENCES, INC. (US) 2024-03-19 US disclosed
CN-112236416-B Pyrimidine cyclohexenyl glucocorticoid receptor modulators 科赛普特治疗公司 2024-03-01 CN disclosed
WO-2023148277-A1 AGENTS AND METHODS FOR TARGETED DELIVERY OF NUCLEIC ACIDS TO CELLS BioNTech SE (DE) 2023-08-10 WO disclosed
WO-2023148276-A1 AGENTS AND METHODS FOR TARGETED DELIVERY TO CELLS BioNTech SE (DE) 2023-08-10 WO disclosed
US-20230183186-A1 PYRIMIDINE CYCLOHEXENYL GLUCOCORTICOID RECEPTOR MODULATORS CORCEPT THERAPEUTICS INCORPORATED 2023-06-15 US disclosed
US-4847429-A ALKYLATION, ACID CATALYSTS, DEHYDROGENATION EASTMAN KODAK COMPANY (US) 1989-07-11 US disclosed
WO-1989000987-A1 PROCESS FOR PRODUCING PHENYLHYDROQUINONES EASTMAN KODAK COMPANY (US) 1989-02-09 WO disclosed
US-4317932-A Preparation of secondary amines W. R. GRACE & CO. (US) 1982-03-02 US disclosed
US-4252707-A AMINE SALT, WATER-THINNABLE RUID JOHN O 1981-02-24 US disclosed
US-4250964-A INJECTING CYCLOHEXENE OR CYCLOHEXADIENE TO REDUCE VISCOSITY GULF RESEARCH & DEVELOPMENT COMPANY (US) 1981-02-17 US disclosed
US-3945837-A RESINOUS BINDER, HYDROCARBON SOLVENT, MODIFIED DYE SAKURA COLOR PRODUCTS CORPORATION (JA) 1976-03-23 US disclosed
US-3929677-A Perfume compositions and perfurme articles containing one isomer of an octahydrotetramethyl acetonaphthone INT FLAVORS & FRAGRANCES INC 1975-12-30 US disclosed
US-3911018-A Novel process and products produced by said process INT FLAVORS & FRAGRANCES INC 1975-10-07 US disclosed
US-3907321-A Novel tobacco product comprising one or more isomers of an octahydrotetramethyl acetonaphthone INT FLAVORS & FRAGRANCES INC 1975-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11945808-B2 Substituted cyclohexyl compounds as NOP inhibitors OPRL1, OPRK1, NOP56 ALDH1A1 2958/4885ALOX15 3104/4885PKM 2911/4885
US-20230183186-A1 PYRIMIDINE CYCLOHEXENYL GLUCOCORTICOID RECEPTOR MODULATORS NR3C1, NR3C2, MC2R ALDH1A1 3630/4885ALOX15 1388/4885PKM 3323/4885
US-11932601-B2 Immunoregulatory agents IDO1, IDO2, INMT ALDH1A1 219/4885ALOX15 101/4885PKM 3394/4885
US-12018001-B2 Pyrimidine cyclohexenyl glucocorticoid receptor modulators NR3C1, NR3C2, MC2R ALDH1A1 3551/4885ALOX15 1198/4885PKM 3302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.