O-Tolylamine

O-Tolylamine

SCHEMBL7248185

Cc1ccccc1N.O=C(O)c1ccccc1C(=O)c1ccccc1O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.59
CYP3A4 P08684 2/20 0.59
CYP2C9 P11712 1/20 0.59
ALDH1A1 P00352 7/20 0.58
KDM4E B2RXH2 3/20 0.52
HPGD P15428 3/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
HMGB1 P09429 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
CA14 Q9ULX7 1/20 0.52
AKR1C3 P42330 2/20 0.46
MYC P01106 1/20 0.46
HSD17B10 Q99714 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylic Acid SCHEMBL10362316 0.90 ALDH1A1 (0.64) KMT2ACYP3A4CYP2C9ALDH1A1KDM4E
Methyl Alcohol SCHEMBL8606279 0.83 ALDH1A1 (0.68) KMT2ACYP3A4CYP2C9ALDH1A1KDM4E
SCHEMBL1334176 0.83 ALDH1A1 (0.74) KMT2ACYP3A4CYP2C9ALDH1A1KDM4E
Salicylic Acid SCHEMBL8206594 0.81 ALDH1A1 (0.56) KMT2ACYP3A4CYP2C9ALDH1A1KDM4E
SCHEMBL11665831 0.81 ALDH1A1 (0.71) KMT2ACYP3A4CYP2C9ALDH1A1KDM4E
Dimethylamine SCHEMBL6883348 0.80 ALDH1A1 (0.63) KMT2ACYP3A4CYP2C9ALDH1A1KDM4E
O-Tolylamine SCHEMBL27673299 0.78 KDM4E (0.58) KMT2ACYP3A4CYP2C9ALDH1A1KDM4E
SCHEMBL3358950 0.77 SPR (0.56) KMT2ACYP3A4CYP2C9ALDH1A1KDM4E
SCHEMBL357669 0.77 CYP3A4 (0.72) KMT2ACYP3A4CYP2C9ALDH1A1KDM4E
SCHEMBL2028031 0.77 MAPT (0.67) KMT2ACYP3A4CYP2C9ALDH1A1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6635602-B1 Heat sensitive and pressure sensitive recording material; synthesised directly by the reaction of two derivatives of amino phenols, phthalic anhydrides, keto acids and/or diphenylamines with a phenol derivative CIBA SPECIALTY CHEMICALS CORPORATION 2003-10-21 US disclosed