Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7253237 | 0.91 | TACR1 (0.42) | SIGMAR1ALDH1A1TACR1 | |
| SCHEMBL7246639 | 0.78 | FPR2 (0.43) | DRD2DRD4SIGMAR1PREPTACR1 | |
| Trifluoroacetic Acid SCHEMBL19613522 | 0.72 | DRD2 (0.49) | DRD2DRD4SIGMAR1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL19613524 | 0.72 | DRD2 (0.49) | DRD2DRD4SIGMAR1KMT2AALDH1A1 | |
| SCHEMBL7543008 | 0.69 | SIGMAR1 (0.45) | LMNADRD4SIGMAR1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL9038823 | 0.67 | S1PR5 (0.67) | KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL2267986 | 0.67 | SIGMAR1 (0.57) | LMNASIGMAR1KMT2AALDH1A1MEN1 | |
| Trifluoroacetic Acid SCHEMBL2267982 | 0.67 | SIGMAR1 (0.57) | LMNASIGMAR1KMT2AALDH1A1MEN1 | |
| Trifluoroacetic Acid SCHEMBL2269036 | 0.66 | ALDH1A1 (0.57) | LMNADPP7SIGMAR1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL29977328 | 0.66 | S1PR5 (0.48) | LMNASIGMAR1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6525044-B2 | Treatment of neurological disorders related to beta -amyloid production such as Alzheimer's disease and Down's Syndrome. | BRISTOL-MYERS SQUIBB COMPANY | 2003-02-25 | — | — | US | disclosed |
| US-20020055501-A1 | Succinoylamino carbocycles and heterocycles as inhibitors of a-beta protein production | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020055501-A1 | Succinoylamino carbocycles and heterocycles as inhibitors of a-beta protein production | APP, APH1A, APH1B | CPB2 402/4885LMNA 570/4885DRD2 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.