Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ME1 | P48163 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259783 | 0.75 | POLB (0.63) | POLBMEN1KMT2AMAPTTHRB | |
| SCHEMBL7469304 | 0.72 | POLB (0.55) | POLBMEN1KMT2AMAPTTHRB | |
| SCHEMBL5167815 | 0.71 | ALDH1A1 (0.43) | POLBMEN1KMT2AMAPTTHRB | |
| SCHEMBL5169747 | 0.70 | LMNA (0.51) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10858951 | 0.70 | ACE (0.43) | POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL11276340 | 0.70 | CA2 (0.38) | POLBMEN1KMT2AMAPTTHRB | |
| SCHEMBL6032173 | 0.70 | MAPT (0.54) | POLBMEN1KMT2AMAPTTHRB | |
| Bromide SCHEMBL11277120 | 0.69 | CA2 (0.37) | POLBMEN1KMT2AMAPTTHRB | |
| SCHEMBL6037064 | 0.69 | POLB (0.58) | POLBMEN1KMT2AMAPTTHRB | |
| SCHEMBL7291421 | 0.67 | CYP2C19 (0.41) | POLBMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003029251-A1 | NOVEL PROCESS FOR THE SYNTHESIS OF THIAZOLIDINEDIONE DERIVATIVES | BIOCON LIMITED (IN) | 2003-04-10 | — | — | WO | disclosed |