SCHEMBL7253358

SCHEMBL7253358

CCC1CC[C@@]2(C)C(CC=C3[C@@H]4CC[C@H]([C@H](C)CCCC(C)C)[C@@]4(C)CC[C@@H]32)C1

nearest known ligand 0.76

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.76
▸ KMT2A Q03164 2/20 0.76
▸ ALDH1A1 P00352 2/20 0.76
▸ USP2 O75604 2/20 0.76
▸ MAPT P10636 1/20 0.76
▸ ALOX15 P16050 1/20 0.76
▸ DHCR24 Q15392 10/20 0.57
▸ TRPV1 Q8NER1 1/20 0.50
▸ THRB P10828 1/20 0.46
▸ LMNA P02545 1/20 0.43
▸ ABCB1 P08183 1/20 0.43
▸ OSBP P22059 1/20 0.43
▸ RORC P51449 1/20 0.43
▸ OSBP2 Q969R2 1/20 0.43
▸ CYP46A1 Q9Y6A2 1/20 0.43
▸ CYP3A4 P08684 1/20 0.43
▸ CDC25A P30304 1/20 0.42
▸ CDC25B P30305 1/20 0.42
▸ SRD5A1 P18405 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7247289 0.87 USP2 (0.79) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL28459060 0.86 MEN1 (0.77) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL28606202 0.86 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL14360754 0.86 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL15529878 0.86 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL25035233 0.86 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL1957035 0.86 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL187737 0.86 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL22099724 0.86 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL5571689 0.86 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030004148-A1 Regulation of meiosis NOVO NORDISK A/S (DK) 2003-01-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030004148-A1 Regulation of meiosis ALPG, MNS1, BUB1B MEN1 1455/4885KMT2A 1368/4885ALDH1A1 2659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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