Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581979 | 0.78 | ENPP2 (0.80) | MAPTALDH1A1LMNAENPP2SMN1; SMN2 | |
| SCHEMBL3044836 | 0.75 | MAPT (0.69) | MAPTALDH1A1LMNAENPP2SMN1; SMN2 | |
| SCHEMBL3893386 | 0.73 | MAPT (0.62) | MAPTALDH1A1LMNAENPP2SMN1; SMN2 | |
| SCHEMBL315992 | 0.72 | ALDH1A1 (0.69) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL7253846 | 0.72 | HSD11B1 (0.47) | MAPTALDH1A1LMNAENPP2SMN1; SMN2 | |
| SCHEMBL942925 | 0.71 | MAPT (0.69) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL3147292 | 0.70 | MAPT (0.88) | MAPTALDH1A1LMNAENPP2SMN1; SMN2 | |
| SCHEMBL594206 | 0.70 | MAPT (1.00) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL2550023 | 0.70 | MAPT (0.72) | MAPTALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL15722399 | 0.70 | ALDH1A1 (0.69) | MAPTALDH1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613769-B1 | Incubating samples with enzyme inhibitors, then determining complexes formed; medical diagnosis; therapy for allergies and inflammation | Max-Planck-Gesellschaft zur Föderung der Wissenschaften. e.V. (DE) | 2003-09-02 | — | — | US | disclosed |