Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 3/20 | 0.59 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.58 |
| ▸ | AMD1 | P17707 | 3/20 | 0.54 |
| ▸ | NADK | O95544 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GAPDH | P04406 | 1/20 | 0.52 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472571 | 0.90 | HSPA8 (0.72) | HSPA5HSPA8RXFP1HSD17B10GAPDH | |
| SCHEMBL472569 | 0.90 | HSPA8 (0.72) | HSPA5HSPA8RXFP1HSD17B10GAPDH | |
| SCHEMBL7254007 | 0.85 | EGFR (0.60) | HSPA5HSPA8RXFP1HSD17B10GAPDH | |
| SCHEMBL6825589 | 0.79 | HSPA8 (0.61) | HSPA5HSPA8RXFP1HSD17B10GAPDH | |
| SCHEMBL7258842 | 0.77 | ADORA3 (0.69) | HSPA5HSPA8RXFP1HSD17B10GAPDH | |
| SCHEMBL7258849 | 0.77 | ADORA3 (0.69) | HSPA5HSPA8RXFP1HSD17B10GAPDH | |
| SCHEMBL13835108 | 0.77 | GAPDH (0.84) | HSPA5HSPA8AMD1NADKHSD17B10 | |
| SCHEMBL7258953 | 0.76 | GAPDH (0.70) | HSPA5HSPA8AMD1NADKRXFP1 | |
| SCHEMBL7253995 | 0.76 | HSPA8 (0.66) | HSPA5HSPA8RXFP1HSD17B10GAPDH | |
| SCHEMBL7254002 | 0.76 | HSPA8 (0.66) | HSPA5HSPA8RXFP1HSD17B10GAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051881-A1 | SUBSTITUTED PURINE NUCLEOSIDE LIBRARIES AND COMPOUNDS BY SOLID-PHASE COMBINATORIAL STRATEGIES | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |