Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 15/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785176 | 0.85 | HPGD (0.67) | KCNMA1POLBKDM4EMEN1KMT2A | |
| SCHEMBL13329852 | 0.84 | MEN1 (0.62) | POLBMEN1KMT2AHPGDGAA | |
| SCHEMBL3327166 | 0.83 | KCNMA1 (0.54) | KCNMA1POLBKDM4EHIF1AMEN1 | |
| SCHEMBL31458629 | 0.83 | KCNMA1 (0.54) | KCNMA1POLBKDM4EHIF1AMEN1 | |
| SCHEMBL7251675 | 0.83 | HPGD (0.57) | KCNMA1POLBKDM4EHIF1AMEN1 | |
| SCHEMBL7257110 | 0.83 | MEN1 (0.72) | KCNMA1POLBMEN1KMT2AHPGD | |
| SCHEMBL1249700 | 0.81 | KCNMA1 (0.64) | KCNMA1POLBKDM4EHIF1AMEN1 | |
| SCHEMBL8006888 | 0.81 | HPGD (0.72) | KCNMA1POLBMEN1KMT2AHPGD | |
| SCHEMBL28295632 | 0.81 | KCNMA1 (0.68) | KCNMA1POLBMEN1KMT2AHPGD | |
| SCHEMBL2095473 | 0.80 | HPGD (0.58) | KDM4EMEN1KMT2AHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6635091-B2 | Oxidation color dye and coupler | L'OREAL S. A. (FR) | 2003-10-21 | — | — | US | claimed |
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | L'OREAL SA (FR) | 2002-12-05 | — | — | US | claimed |
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | claimed |
| US-6635091-B2 | Oxidation color dye and coupler | L'OREAL S. A. (FR) | 2003-10-21 | — | — | US | disclosed |
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | L'OREAL SA (FR) | 2002-12-05 | — | — | US | disclosed |
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | KRT18, FH, FGB | KCNMA1 928/4885POLB 60/4885KDM4E 868/4885 |
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | FH, KRT18, CYB5R3 | KCNMA1 1647/4885POLB 123/4885KDM4E 1443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.