Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 1/20 | 0.30 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259062 | 0.87 | HTR4 (0.40) | DRD2 | |
| SCHEMBL7257990 | 0.82 | KCNH2 (0.41) | KCNH2AKT1DRD2HSP90AA1HSP90AB1 | |
| Hydrochloric Acid SCHEMBL7254030 | 0.82 | SLC6A2 (0.40) | — | |
| SCHEMBL7257987 | 0.72 | DRD2 (0.44) | KCNH2DRD2 | |
| SCHEMBL7254208 | 0.71 | KCNH2 (0.41) | KCNH2DRD2TLR9TLR8TLR7 | |
| SCHEMBL6328978 | 0.71 | HTR4 (0.54) | — | |
| SCHEMBL4437515 | 0.69 | HTR4 (0.54) | — | |
| SCHEMBL7254150 | 0.69 | HTR4 (0.45) | — | |
| SCHEMBL7257840 | 0.69 | DRD2 (0.35) | KCNH2DRD2 | |
| SCHEMBL7254109 | 0.64 | SLC6A2 (0.47) | AKT1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057688-A2 | OXO OR OXY-PYRIDINE COMPOUNDS AS 5-HT4 RECEPTOR MODULATORS | PFIZER JAPAN INC. (JP) | 2003-07-17 | — | — | WO | disclosed |