Indole

Indole

SCHEMBL7260953

c1ccc2[nH]ccc2c1.c1cocn1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 7/20 0.59
TRPA1 O75762 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
ITGB2 P05107 1/20 0.59
ICAM1 P05362 1/20 0.59
ITGAL P20701 1/20 0.59
CA4 P22748 1/20 0.59
CA6 P23280 1/20 0.59
ADK P55263 1/20 0.59
NPC1 O15118 1/20 0.36
AXL P30530 1/20 0.35
NUDT1 P36639 1/20 0.35
NISCH Q9Y2I1 1/20 0.33
PIK3CD O00329 1/20 0.33
CYP17A1 P05093 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
ALDH1A1 P00352 1/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indole SCHEMBL27856584 0.89 TRPA1 (0.46) AHRTRPA1CA1CA2ITGB2
Quinoline SCHEMBL28798085 0.89 ALDH1A1 (0.46) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL27621647 0.85 TRPA1 (0.42) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL27393259 0.79 AHR (0.77) AHRTRPA1CA1CA2ITGB2
Naphthalene SCHEMBL303948 0.79 CYP2A6 (0.40) CYP17A1CYP11B1CYP11B2ALDH1A1CYP2A6
Naphthalene SCHEMBL9615518 0.79 CYP2A6 (0.40) CYP17A1CYP11B1CYP11B2ALDH1A1CYP2A6
Indole SCHEMBL6157061 0.77 AHR (0.74) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL7026553 0.77 AHR (0.90) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL6702023 0.77 AHR (0.90) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL30250492 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101068791-B Method for preparing salt with tetrafluoroborate anion and reducing the content of hologenate MERCK PATENT GMBH 2010-12-08 CN claimed
CN-101841005-A Novel organic compound and organic light emitting device using the same LG CHEMICAL LTD 2010-09-22 CN claimed
CN-1839129-A Novel n-substituted indolyl-3-glyoxylic acid amides, use thereof as a medicament, and method for the production thereof ZENTARIS GMBH (DE) 2006-09-27 CN claimed
CN-1105030-C Thermal waterless lithographic printing plate KODAK POLYCHROME GRAPHICS CO (US) 2003-04-09 CN claimed
CN-1269752-A Thermal waterless lithographic printing plate KODAK POLYCHROME GRAPHICS CO (US) 2000-10-11 CN claimed
CN-115124505-B Indole alkaloid compound and preparation method and application thereof 云南中烟工业有限责任公司 2023-07-18 CN disclosed
CN-113185503-B Natural product Pimpirinine derivative and preparation method and application thereof 南京农业大学 2023-02-28 CN disclosed
CN-115462383-A Application of Almazole D alkaloid and derivatives thereof in resisting plant viruses and pathogenic bacteria 河北工业大学 2022-12-13 CN disclosed
CN-115433176-A Almazole D alkaloid derivative containing thiourea structure and preparation method and application thereof 河北工业大学 2022-12-06 CN disclosed
CN-115124505-A Indole alkaloid compound and preparation method and application thereof 云南中烟工业有限责任公司 2022-09-30 CN disclosed
CN-105705697-B Floating linear tension member comprising a plurality of fibers 帝人芳纶有限公司 2022-02-08 CN disclosed
CN-113185503-A Natural product Pimpirinine derivative and preparation method and application thereof 南京农业大学 2021-07-30 CN disclosed
CN-100528561-C Imageable element, method of forming image, and image prepared thereby EASTMAN KODAK CO (US) 2009-08-19 CN disclosed
CN-101379070-A Oxonium and sulfonium salts MERCK PATENT GMBH (DE) 2009-03-04 CN disclosed
CN-100448669-C Imageable element comprising sulfated polymers KODAK POLYCHROME GRAPHICS LLC (US) 2009-01-07 CN disclosed
CN-1839129-A Novel n-substituted indolyl-3-glyoxylic acid amides, use thereof as a medicament, and method for the production thereof ZENTARIS GMBH (DE) 2006-09-27 CN disclosed
CN-1816446-A Imageable elements comprising sulfated polymers KODAK POLYCHROME GRAPHICS LLC (US) 2006-08-09 CN disclosed
CN-1816543-A Indole derivatives having apoptosis-inducing effect ZENTARIS GMBH (DE) 2006-08-09 CN disclosed
CN-1253451-C Novel indodyl oxazole compound and its prepn. and application UNIV FUDAN (CN) 2006-04-26 CN disclosed
WO-2003106438-A1 SYNTHESIS OF DIAZONAMIDE \"A\" CORE THE SCRIPPS RESEARCH INSTITUTE (US) 2003-12-24 WO disclosed