Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | BAX | Q07812 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | FURIN | P09958 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458231 | 0.85 | ALDH1A1 (0.41) | LTA4HMAOBTSHRMEN1MITF | |
| SCHEMBL381634 | 0.80 | LTA4H (0.57) | LTA4HMAOBTSHRMEN1KMT2A | |
| SCHEMBL29411044 | 0.77 | ACHE (0.50) | MAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL24031 | 0.77 | ACHE (0.50) | MAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL22559 | 0.77 | LTA4H (0.75) | LTA4HMAOBTSHRAKR1C3MEN1 | |
| SCHEMBL1173711 | 0.77 | LTA4H (0.75) | LTA4HMAOBTSHRAKR1C3MEN1 | |
| SCHEMBL30018242 | 0.77 | LTA4H (0.75) | LTA4HMAOBTSHRAKR1C3MEN1 | |
| SCHEMBL4025817 | 0.77 | LTA4H (0.75) | LTA4HMAOBTSHRAKR1C3MEN1 | |
| SCHEMBL30211827 | 0.77 | LTA4H (0.75) | LTA4HMAOBTSHRAKR1C3MEN1 | |
| SCHEMBL1173869 | 0.77 | LTA4H (0.75) | LTA4HMAOBTSHRAKR1C3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068738-A1 | PYRROLE DERIVATIVES AS LIGANDS OF MELANOCORTIN RECEPTORS | NEUROCRINE BIOSCIENCES, INC. (US) | 2003-08-21 | — | — | WO | disclosed |