Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478967 | 0.91 | TACR1 (0.40) | ALDH1A1TACR1CTSLCTSBCTSK | |
| SCHEMBL3834075 | 0.83 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1 | |
| SCHEMBL5547411 | 0.80 | GLA (0.41) | EGFRSIGMAR1ALDH1A1KMT2A | |
| SCHEMBL3916786 | 0.80 | AGTR2 (0.43) | CTSLCTSBCTSK | |
| SCHEMBL9024007 | 0.78 | NR1D1 (0.39) | KMT2A | |
| SCHEMBL7264621 | 0.77 | SIGMAR1 (0.37) | SIGMAR1 | |
| SCHEMBL5547419 | 0.77 | EGFR (0.41) | EGFRSIGMAR1ALDH1A1KMT2A | |
| SCHEMBL8478663 | 0.76 | EGFR (0.49) | EGFRALDH1A1KMT2A | |
| SCHEMBL5800349 | 0.76 | SIGMAR1 (0.38) | SIGMAR1 | |
| SCHEMBL20997586 | 0.76 | FOLH1 (0.40) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38329-E1 | Chelated complexes of paramagnetic metals with low toxicity | BRACCO IMAGING S.P.A. (IT) | 2003-11-25 | — | — | US | disclosed |
| US-6177562-B1 | Chelated complexes of paramagnetic metals with low toxicity | DIBRA S.P.A. (IT) | 2001-01-23 | — | — | US | disclosed |