Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478967 | 0.84 | TACR1 (0.40) | NR1D1TEAD3AGTR2 | |
| SCHEMBL9024977 | 0.82 | SIGMAR1 (0.35) | — | |
| SCHEMBL18807567 | 0.78 | FOLH1 (0.34) | — | |
| SCHEMBL16644695 | 0.78 | CHIT1 (0.37) | — | |
| SCHEMBL18807569 | 0.78 | L3MBTL1 (0.38) | MEN1KMT2A | |
| SCHEMBL9906195 | 0.78 | CHIT1 (0.37) | — | |
| SCHEMBL10060134 | 0.78 | CHIT1 (0.37) | — | |
| SCHEMBL19389406 | 0.78 | L3MBTL1 (0.38) | MEN1KMT2A | |
| SCHEMBL3834075 | 0.78 | SIGMAR1 (0.47) | AGTR2 | |
| SCHEMBL7265773 | 0.78 | EGFR (0.45) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438206-B1 | 6-Ring-containing macrocyclic tetraaza compounds, processes for their preparation, and pharmaceutical agents containing them | SCHERING AG (DE) | 1996-08-21 | — | — | EP | disclosed |
| US-5403572-A | Macrocyclic polyaza compounds containing 5 or 6 membered rings, process for producing them and pharmaceutical media containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-04-04 | — | — | US | disclosed |
| US-5334371-A | Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-08-02 | — | — | US | disclosed |
| EP-0438206-A1 | 6-Ring-containing macrocyclic tetraaza compounds, processes for their preparation, and pharmaceutical agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-07-24 | — | — | EP | disclosed |