Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834075 | 0.91 | SIGMAR1 (0.47) | AGTR2ALDH1A1 | |
| SCHEMBL7265773 | 0.91 | EGFR (0.45) | TACR1CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL3916786 | 0.85 | AGTR2 (0.43) | SLC6A9CTSLCTSBCTSKAGTR2 | |
| SCHEMBL9024007 | 0.84 | NR1D1 (0.39) | TEAD3AGTR2NR1D1 | |
| SCHEMBL6858941 | 0.83 | FOLH1 (0.44) | — | |
| SCHEMBL3000798 | 0.83 | FOLH1 (0.44) | — | |
| SCHEMBL13567995 | 0.78 | L3MBTL1 (0.46) | ALDH1A1 | |
| SCHEMBL7573297 | 0.78 | SIGMAR1 (0.56) | ALDH1A1 | |
| SCHEMBL19590904 | 0.77 | DPP4 (0.43) | — | |
| SCHEMBL9032439 | 0.75 | FOLH1 (0.45) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922862-A | Process for the preparation of tetraazamacrocycles | DIBRA S.P.A. (IT) | 1999-07-13 | — | — | US | claimed |
| US-5922862-A | Process for the preparation of tetraazamacrocycles | DIBRA S.P.A. (IT) | 1999-07-13 | — | — | US | disclosed |