Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.41 |
| ▸ | PGC | P20142 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268400 | 0.91 | CTSK (0.34) | REN | |
| SCHEMBL7268382 | 0.86 | REN (0.46) | RENPGC | |
| SCHEMBL7269885 | 0.79 | REN (0.45) | REN | |
| SCHEMBL7274796 | 0.78 | REN (0.46) | REN | |
| SCHEMBL7268413 | 0.78 | CTSK (0.38) | RENPGC | |
| SCHEMBL7370857 | 0.77 | REN (0.54) | RENPGC | |
| SCHEMBL7443816 | 0.75 | REN (0.55) | RENPGC | |
| SCHEMBL9725848 | 0.74 | REN (0.53) | RENPGC | |
| SCHEMBL9725846 | 0.74 | REN (0.53) | RENPGC | |
| SCHEMBL7303652 | 0.74 | REN (0.57) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |