SCHEMBL4207227

SCHEMBL4207227

COc1ccc(S(N)(=O)=O)c(OC)c1OC

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.49
CA1 P00915 6/20 0.49
CA12 O43570 6/20 0.49
CA9 Q16790 6/20 0.49
PKM P14618 2/20 0.49
KDM4E B2RXH2 1/20 0.48
MAPT P10636 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 2/20 0.41
POLB P06746 1/20 0.41
KMT2A Q03164 1/20 0.41
CA5A P35218 1/20 0.41
CA14 Q9ULX7 1/20 0.41
PTGS1 P23219 1/20 0.40
PTGS2 P35354 1/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4608472 0.85 PKM (0.46) CA2CA1CA12CA9PKM
SCHEMBL20549321 0.85 ALDH1A1 (0.49) CA2CA1CA12CA9PKM
Hydrochloric Acid SCHEMBL4609743 0.83 PKM (0.45) CA2CA1CA12CA9PKM
SCHEMBL28301192 0.83 MAPT (0.50) CA2CA1CA12CA9PKM
SCHEMBL791503 0.82 CA2 (0.50) CA2CA1CA12CA9PKM
SCHEMBL4609359 0.80 PKM (0.43) CA2CA1CA12CA9PKM
SCHEMBL2494766 0.80 TRPV4 (0.55) KDM4EMAPTTDP1ALDH1A1POLB
SCHEMBL7269471 0.80 MAPT (0.46) KDM4EMAPTTDP1ALDH1A1POLB
SCHEMBL691733 0.80 ALDH1A1 (0.56) CA2CA1CA12CA9PKM
SCHEMBL1939161 0.80 PDIA6 (0.42) CA2CA1CA12CA9PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0694041-A1 A PROCESS AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS CONTAINING N-ALPHA-METHYLARGININE THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-01-31 EP claimed
WO-1994022911-A2 A PROCESS AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS CONTAINING Nα-METHYLARGININE THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-10-13 WO claimed
EP-4605011-A2 POLYPEPTIDYL LINKERS Quantum-Si Incorporated (US) 2025-08-27 EP disclosed
EP-4396354-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF Wave Life Sciences Ltd. (SG) 2024-07-10 EP disclosed
WO-2024145435-A2 LIPID COMPOSITIONS AND METHODS FOR DELIVERY TO IMMUNE CELLS Life Technologies Corporation (US) 2024-07-04 WO disclosed
WO-2024130218-A1 STAPLED PEPTIDES AND METHODS THEREOF FOG PHARMACEUTICALS, INC. (US) 2024-06-20 WO disclosed
EP-4370503-A1 ESTERS OF A RETINOID AND BAKUCHIOL AND PREPARATIONS THEREOF Conagen Inc. (US) 2024-05-22 EP disclosed
WO-2024097746-A1 ALKENE CYCLOPROPANATION WITH NICKEL CATALYST ENHANCER AND IMPROVED REARRANGEMENT REACTION CONAGEN INC. (US) 2024-05-10 WO disclosed
WO-2024086826-A2 POLYPEPTIDYL LINKERS Quantum-Si Incorporated (US) 2024-04-25 WO disclosed
EP-4337639-A1 NAMPT INHIBITORS AND USES THEREOF Remedy Plan, Inc. (US) 2024-03-20 EP disclosed
WO-2024050554-A2 SYNTHESIS OF COTYLENIN AND ANALOGS THEREOF FOR THE DEVELOPMENT OF SELECTIVE MODULATORS OF 14-3-3 PROTEIN-PROTEIN INTERACTION UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-03-07 WO disclosed
CN-105753965-A Conjugate Based Systems For Controlled Drug Delivery 斯马特塞尔斯公司 2016-07-13 CN disclosed
CN-105705143-A Nucleic acid nanostructures for in vivo agent delivery 达娜-法勃肿瘤研究所公司 2016-06-22 CN disclosed
CN-105492460-A Stabilized polypeptide insulin receptor modulators HARVARD COLLEGE 2016-04-13 CN disclosed
CN-104936595-A Methods and compositions for locally increasing body fat TOPOKINE THERAPEUTICS INC 2015-09-23 CN disclosed
CN-104640844-A Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates-2-formate DOW AGROSCIENCES LLC 2015-05-20 CN disclosed
CN-103038240-A Synthetic method for preparing ecteinascidin compounds PHARMA MAR SA 2013-04-10 CN disclosed
US-20090030038-A1 Novel 8-Sulfonylamino-3 Aminosubstituted Chroman or Tetrahydronaphtalene Derivatives Modulating the 5Ht6 Receptor ASTRAZENECA AB (SE) 2009-01-29 US disclosed
EP-0694041-A1 A PROCESS AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS CONTAINING N-ALPHA-METHYLARGININE THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-01-31 EP disclosed
WO-1994022911-A2 A PROCESS AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS CONTAINING Nα-METHYLARGININE THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030038-A1 Novel 8-Sulfonylamino-3 Aminosubstituted Chroman or Tetrahydronaphtalene Derivatives Modulating the 5Ht6 Receptor HTR6, HTR1A, HTR1D CA2 3446/4885CA1 4098/4885CA12 4343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.