Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275454 | 0.87 | CCR1 (0.45) | CCR1POLBNPC1KCNH2DPP4 | |
| SCHEMBL7271874 | 0.86 | CCR1 (0.50) | CCR1 | |
| SCHEMBL7272937 | 0.86 | NPC1 (0.56) | POLBNPC1KCNH2KMT2A | |
| SCHEMBL7267087 | 0.84 | ALDH1A1 (0.48) | CCR1DPP4MEN1KMT2A | |
| SCHEMBL7272151 | 0.84 | MLYCD (0.42) | CCR1POLBKCNH2OPRD1DPP4 | |
| SCHEMBL10584481 | 0.82 | NPC1 (0.38) | CCR1POLBNPC1KCNH2SLC6A2 | |
| SCHEMBL7284635 | 0.81 | OPRD1 (0.44) | KCNH2OPRD1DPP4 | |
| SCHEMBL7272889 | 0.80 | SIGMAR1 (0.43) | POLBNPC1KCNH2SLC6A2SLC6A4 | |
| SCHEMBL7271931 | 0.79 | KCNH2 (0.53) | KCNH2OPRD1DPP4 | |
| SCHEMBL7267029 | 0.75 | KMT2A (0.45) | NPC1DPP4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340832-A | Prolinal derivatives useful for treating amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-08-23 | — | — | US | claimed |
| EP-0268190-B1 | PROLINAL DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | claimed |
| EP-0268190-A1 | Prolinal derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-05-25 | — | — | EP | claimed |
| US-5254550-A | Enzyme inhibitor | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-10-19 | — | — | US | disclosed |
| US-4956380-A | COGNITION ACTIVATORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |