Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284219 | 0.85 | FAAH (0.45) | TDP1L3MBTL1ALDH1A1TSHRMMP1 | |
| SCHEMBL7275007 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRSMN1; SMN2POLBSIRT5 | |
| SCHEMBL7285181 | 0.75 | TDP1 (0.45) | TDP1L3MBTL1ALDH1A1TSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7283160 | 0.73 | POLB (0.42) | ALDH1A1SMN1; SMN2MMP2POLBSIRT5 | |
| Trifluoroacetic Acid SCHEMBL8881152 | 0.71 | SIGMAR1 (0.40) | POLBSIRT5 | |
| SCHEMBL45050 | 0.70 | TDP1 (0.86) | TDP1L3MBTL1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL30371663 | 0.70 | TDP1 (0.86) | TDP1L3MBTL1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7284234 | 0.69 | FAAH (0.48) | POLB | |
| SCHEMBL2567758 | 0.67 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7983366 | 0.67 | CHRNB2 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |