Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280208 | 0.93 | LTA4H (0.43) | LTA4HHDAC1ALDH1A1SIGMAR1MEN1 | |
| SCHEMBL7281870 | 0.92 | TPSAB1 (0.39) | LTA4HHDAC1ALDH1A1SIGMAR1KLKB1 | |
| SCHEMBL7282210 | 0.90 | SIGMAR1 (0.44) | LTA4HALDH1A1SIGMAR1MEN1CYP1A2 | |
| SCHEMBL7283915 | 0.90 | SIGMAR1 (0.41) | LTA4HALDH1A1SIGMAR1MEN1CYP1A2 | |
| SCHEMBL7272956 | 0.89 | MMP2 (0.41) | HDAC1ALDH1A1SIGMAR1MTNR1ASMN1; SMN2 | |
| SCHEMBL7284039 | 0.89 | ITGB3 (0.42) | HDAC1ALDH1A1KLKB1SMN1; SMN2TSHR | |
| SCHEMBL7281757 | 0.89 | MMP2 (0.41) | HDAC1ALDH1A1SIGMAR1MTNR1ASMN1; SMN2 | |
| SCHEMBL7281946 | 0.89 | MMP2 (0.41) | HDAC1ALDH1A1SIGMAR1MTNR1ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7289827 | 0.88 | ALDH1A1 (0.39) | LTA4HHDAC1ALDH1A1SIGMAR1MEN1 | |
| Water SCHEMBL7275704 | 0.88 | LTA4H (0.40) | LTA4HHDAC1ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |