Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 16/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 12/20 | 0.55 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280275 | 0.87 | PDE3B (0.59) | PDE3BPDE3ACYP11B1CYP19A1 | |
| SCHEMBL7290394 | 0.79 | TBXAS1 (0.58) | PDE3BPDE3A | |
| SCHEMBL10648091 | 0.79 | PDE3B (0.43) | PDE3BPDE3ACYP11B1CYP11B2CYP19A1 | |
| SCHEMBL2529997 | 0.77 | CYP11B1 (0.86) | CYP11B1CYP11B2CYP17A1CYP19A1CYP2A6 | |
| SCHEMBL10645457 | 0.76 | CYP11B1 (0.56) | PDE3BPDE3ACYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7280366 | 0.76 | PDE3B (1.00) | PDE3BPDE3A | |
| SCHEMBL1024261 | 0.75 | CYP11B1 (0.84) | CYP11B1CYP11B2CYP17A1CYP19A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL1775141 | 0.74 | CYP11B1 (0.81) | CYP11B1CYP11B2CYP17A1CYP19A1CYP2A6 | |
| SCHEMBL3452908 | 0.73 | LMNA (0.80) | PDE3BPDE3A | |
| SCHEMBL11100630 | 0.72 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP17A1CYP19A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0075436-A1 | Substituted 4,5-dihydro-6-(substituted)-phenyl-3(2H)-pyridazinones and 6-(substituted)phenyl-3(2H)-pyridazinones | WARNER-LAMBERT COMPANY (US) | 1983-03-30 | — | — | EP | claimed |