Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.64 |
| ▸ | DBH | P09172 | 1/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.52 |
| ▸ | HNF4A | P41235 | 2/20 | 0.52 |
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22170762 | 0.81 | HSD17B1 (0.68) | HDAC4HDAC2HDAC8MEN1KMT2A | |
| Tropolone SCHEMBL42739 | 0.78 | — | — | |
| SCHEMBL21471512 | 0.78 | MCL1 (0.52) | MMP2DBHHDAC4HDAC2HDAC8 | |
| SCHEMBL21471507 | 0.76 | HDAC4 (0.69) | MMP2DBHHDAC4HDAC2HDAC8 | |
| Tropolone SCHEMBL9643396 | 0.76 | DBH (0.94) | MMP2DBHHDAC4HDAC2HDAC8 | |
| Tropolone SCHEMBL531387 | 0.76 | DBH (0.94) | MMP2DBHHDAC4HDAC2HDAC8 | |
| Tropolone SCHEMBL9643338 | 0.76 | DBH (0.94) | MMP2DBHHDAC4HDAC2HDAC8 | |
| Tropolone SCHEMBL5969452 | 0.76 | DBH (0.94) | MMP2DBHHDAC4HDAC2HDAC8 | |
| Tropolone SCHEMBL9644163 | 0.76 | DBH (0.94) | MMP2DBHHDAC4HDAC2HDAC8 | |
| Tropolone SCHEMBL9644286 | 0.76 | DBH (0.94) | MMP2DBHHDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073131-A2 | METHOD OF TREATING NEURODEGENERATIVE DISEASES | THE BOARD OF TRUSTEES OF THE UNIVESITY OF ILLINOIS (US) | 2024-04-04 | — | — | WO | disclosed |
| US-20210163393-A1 | HINOKITIOL ANALOGUES, METHODS OF PREPARING AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2021-06-03 | — | — | US | disclosed |
| WO-2019200314-A2 | HINOKITIOL ANALOGUES, METHODS OF PREPARING AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-10-17 | — | — | WO | disclosed |
| CN-101553549-B | Photobase generator and photocurable resin composition | ASAHI KASEI E MATERIALS CORP (JP) | 2013-02-20 | — | — | CN | disclosed |
| US-8137892-B2 | Photobase generator and photocurable resin composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20100151386-A1 | PHOTOBASE GENERATOR AND PHOTOCURABLE RESIN COMPOSITION | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-06-17 | — | — | US | disclosed |
| CN-101553549-A | Photobase generator and photocurable resin composition | ASAHI CHEMICAL CORP (JP) | 2009-10-07 | — | — | CN | disclosed |
| EP-2093269-A1 | PHOTOBASE GENERATOR AND PHOTOCURABLE RESIN COMPOSITION | Asahi Kasei Chemicals Corporation (JP) | 2009-08-26 | — | — | EP | disclosed |
| US-5055356-A | Chelate compound | HITACHI, LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0357219-A1 | Aluminium and aluminium alloy having corrosion-resistant protective layer, and methods of making such a layer | HITACHI, LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163393-A1 | HINOKITIOL ANALOGUES, METHODS OF PREPARING AND PHARMACEUTICAL COMPOSITIONS THEREOF | CYP27A1, CYP27B1, HSD17B7 | MMP2 4356/4885DBH 618/4885HDAC4 1472/4885 |
| US-20100151386-A1 | PHOTOBASE GENERATOR AND PHOTOCURABLE RESIN COMPOSITION | PSMC6, PCNA, POLR2B | MMP2 3435/4885DBH 2447/4885HDAC4 3257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.