Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 13/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284111 | 0.94 | CTSC (0.31) | CTSD | |
| SCHEMBL7293156 | 0.75 | REN (0.53) | REN | |
| SCHEMBL7295284 | 0.75 | REN (0.53) | REN | |
| SCHEMBL9646603 | 0.75 | CTSS (0.42) | REN | |
| SCHEMBL7277008 | 0.74 | REN (0.46) | REN | |
| SCHEMBL7274926 | 0.74 | CTSK (0.47) | RENMMP1MMP2MMP3 | |
| SCHEMBL7277428 | 0.74 | CTSK (0.37) | RENMMP1MMP2MMP3CTSD | |
| SCHEMBL10715871 | 0.73 | CTSS (0.43) | REN | |
| Bromide SCHEMBL10716005 | 0.73 | CTSK (0.36) | RENMMP1MMP2MMP3CTSD | |
| Hydrochloric Acid SCHEMBL7284520 | 0.73 | CTSK (0.36) | RENMMP1MMP2MMP3CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | disclosed |
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | disclosed |