Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283209 | 0.94 | REN (0.34) | CTSD | |
| SCHEMBL10715871 | 0.79 | CTSS (0.43) | — | |
| SCHEMBL7286074 | 0.78 | CTSL (0.42) | — | |
| SCHEMBL30799721 | 0.74 | LTA4H (0.47) | CTSC | |
| SCHEMBL9646165 | 0.73 | CTSK (0.45) | — | |
| SCHEMBL10422480 | 0.73 | REN (0.45) | — | |
| SCHEMBL7282601 | 0.72 | REN (0.42) | — | |
| SCHEMBL7279237 | 0.72 | REN (0.37) | CTSC | |
| SCHEMBL7283971 | 0.72 | REN (0.42) | — | |
| SCHEMBL13079794 | 0.71 | MEN1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | disclosed |
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | disclosed |