Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 17/20 | 0.39 |
| ▸ | PGC | P20142 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284110 | 0.88 | CTSS (0.44) | CTSSCTSKRENPGC | |
| SCHEMBL7363123 | 0.87 | REN (0.43) | CTSSCTSKRENPGC | |
| SCHEMBL10718485 | 0.85 | CTSS (0.47) | CTSSCTSKRENPGC | |
| SCHEMBL7277213 | 0.84 | REN (0.44) | CTSSCTSKREN | |
| SCHEMBL7307303 | 0.80 | CTSS (0.43) | CTSSCTSKRENPGC | |
| SCHEMBL10715988 | 0.80 | REN (0.41) | CTSSCTSKREN | |
| SCHEMBL7274934 | 0.80 | REN (0.45) | CTSSCTSKRENCTSL | |
| SCHEMBL7307293 | 0.80 | CTSS (0.44) | CTSSCTSKRENPGC | |
| SCHEMBL7277678 | 0.80 | MME (0.48) | CTSL | |
| SCHEMBL10718460 | 0.79 | REN (0.47) | CTSSCTSKRENCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | claimed |