Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286158 | 0.91 | MMP2 (0.48) | RENCTSKANPEPERAP1ERAP2 | |
| SCHEMBL7284110 | 0.89 | CTSS (0.44) | RENCTSSCTSK | |
| SCHEMBL10718485 | 0.88 | CTSS (0.47) | RENCTSSCTSK | |
| SCHEMBL7274793 | 0.85 | REN (0.46) | RENANPEPERAP1ERAP2MMP2 | |
| SCHEMBL7283369 | 0.84 | CTSS (0.40) | RENCTSSCTSK | |
| SCHEMBL7277678 | 0.82 | MME (0.48) | MMP2MMP9MMP8 | |
| SCHEMBL10715871 | 0.82 | CTSS (0.43) | RENCTSSCTSK | |
| SCHEMBL7274934 | 0.81 | REN (0.45) | RENCTSSCTSKANPEPERAP1 | |
| SCHEMBL10718705 | 0.81 | REN (0.46) | RENCTSSCTSKANPEPERAP1 | |
| SCHEMBL7307303 | 0.81 | CTSS (0.43) | RENCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | disclosed |