Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 14/20 | 0.42 |
| ▸ | PGC | P20142 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284110 | 0.90 | CTSS (0.44) | CTSSCTSKRENPGCSCN9A | |
| SCHEMBL10718613 | 0.88 | CTSL (0.45) | CTSSCTSKREN | |
| SCHEMBL7277213 | 0.88 | REN (0.44) | CTSSCTSKREN | |
| SCHEMBL7307293 | 0.87 | CTSS (0.44) | CTSSCTSKRENPGC | |
| SCHEMBL7307303 | 0.85 | CTSS (0.43) | CTSSCTSKRENPGC | |
| SCHEMBL7283369 | 0.85 | CTSS (0.40) | CTSSCTSKRENPGC | |
| SCHEMBL10422425 | 0.84 | REN (0.45) | CTSSCTSKRENPGC | |
| SCHEMBL7363123 | 0.83 | REN (0.43) | CTSSCTSKRENPGC | |
| SCHEMBL10715871 | 0.82 | CTSS (0.43) | CTSSCTSKRENPGCSCN9A | |
| SCHEMBL7283203 | 0.82 | CTSL (0.43) | CTSSREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209848-A2 | Enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | claimed |