Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 13/20 | 0.41 |
| ▸ | MMP1 | P03956 | 4/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716030 | 0.82 | ECE1 (0.42) | CTSSCTSK | |
| SCHEMBL10716157 | 0.76 | CTSK (0.47) | RENMMP1MMP13KMT2ACACNA1B | |
| SCHEMBL10715992 | 0.74 | MDM2 (0.38) | RENMEN1KMT2AATMCACNA1B | |
| SCHEMBL10718398 | 0.73 | BACE1 (0.47) | RENCTSSCTSK | |
| SCHEMBL1864929 | 0.72 | REN (0.53) | RENCACNA1BCTSSCTSK | |
| SCHEMBL10715965 | 0.72 | ACE2 (0.53) | CTSSCTSK | |
| SCHEMBL10717459 | 0.70 | CTSS (0.45) | RENKMT2ACTSSCTSK | |
| SCHEMBL10717504 | 0.70 | CTSS (0.45) | RENKMT2ACTSSCTSK | |
| SCHEMBL10717456 | 0.70 | CTSS (0.45) | RENKMT2ACTSSCTSK | |
| SCHEMBL10717422 | 0.70 | MMP1 (0.40) | MMP1MMP13ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | claimed |
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | disclosed |