Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 18/20 | 0.43 |
| ▸ | PGC | P20142 | 1/20 | 0.41 |
| ▸ | CTSE | P14091 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308672 | 0.91 | REN (0.46) | CTSSCTSKRENCTSE | |
| SCHEMBL7363123 | 0.87 | REN (0.43) | CTSSCTSKRENPGC | |
| SCHEMBL10718485 | 0.87 | CTSS (0.47) | CTSSCTSKRENPGC | |
| SCHEMBL7284110 | 0.85 | CTSS (0.44) | CTSSCTSKRENPGC | |
| SCHEMBL7307303 | 0.85 | CTSS (0.43) | CTSSCTSKRENPGCCTSE | |
| SCHEMBL10422425 | 0.84 | REN (0.45) | CTSSCTSKRENPGC | |
| SCHEMBL7303908 | 0.82 | REN (0.49) | CTSKREN | |
| SCHEMBL7277213 | 0.80 | REN (0.44) | CTSSCTSKREN | |
| SCHEMBL7283369 | 0.80 | CTSS (0.40) | CTSSCTSKRENPGC | |
| SCHEMBL10718613 | 0.77 | CTSL (0.45) | CTSSCTSKREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | claimed |