Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | TYR | P14679 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KIF11 | P52732 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725810 | 0.89 | ALDH1A1 (0.75) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL12070412 | 0.83 | MAPT (0.69) | ALDH1A1TAS2R38HSD17B10CYP3A4CYP2C9 | |
| SCHEMBL14872162 | 0.83 | TAS2R38 (0.60) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL1822006 | 0.80 | ALDH1A1 (0.65) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL12071790 | 0.80 | ALDH1A1 (0.62) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| Ammonia Solution, Strong SCHEMBL11429312 | 0.79 | MAPT (0.59) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL5518697 | 0.78 | IDO1 (0.63) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL526059 | 0.78 | MAPT (0.63) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL449122 | 0.78 | ALDH1A1 (0.60) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL11751583 | 0.78 | ALDH1A1 (0.61) | ALDH1A1TP53TYRTSHRTAS2R38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236633-A | Blend of transparent polymer, thiourea and copper compounds | JUJO PAPER CO., LTD. (JP) | 1993-08-17 | — | — | US | claimed |
| US-4264710-A | AN ETHYLENICALLY UNSATURATED COMPOUND, AND A PHOTOPOLYMERIZATION INIATOR | FUJI PHOTO FILM CO., LTD. (JP) | 1981-04-28 | — | — | US | claimed |
| CN-114249702-B | N-aryl- [2,4 '-dithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-114249702-A | N-aryl- [2,4 '-bithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-113631663-A | Sulfonated 2(7) -aminoacridone and 1-aminopyrene dyes and their use as fluorescent labels, in particular for carbohydrate analysis | 马克斯·普朗克科学促进学会 | 2021-11-09 | — | — | CN | disclosed |
| WO-2011152471-A2 | RECHARGEABLE BATTERY, FUNCTIONAL POLYMER, AND METHOD FOR SYNTHESIS THEREOF | 株式会社ポリチオン (JP) | 2011-12-08 | — | — | WO | disclosed |
| US-20100298340-A1 | Thiazol-Guanidine Derivatives Useful As A (Beta)-Related Pathologies | ASTRAZENECA AB (SE) | 2010-11-25 | — | — | US | disclosed |
| CN-101466692-A | Thiazol-guanidine derivatives useful as a (beta) - related pathologies | ASTRAZENECA AB (SE) | 2009-06-24 | — | — | CN | disclosed |
| EP-2010508-A1 | THIAZOL-GUANIDINE DERIVATIVES USEFUL AS A (BETA)- RELATED PATHOLOGIES | AstraZeneca AB (SE) | 2009-01-07 | — | — | EP | disclosed |
| US-20080227895-A1 | Fire retardant vinyl chloride-based resin composition and molded article thereof | MITSUBISHI PLASTICS, INC. (JP) | 2008-09-18 | — | — | US | disclosed |
| WO-2007120096-A1 | THIAZOL-GUANIDINE DERIVATIVES USEFUL AS A (BETA)- RELATED PATHOLOGIES | ASTRAZENECA AB (SE) | 2007-10-25 | — | — | WO | disclosed |
| CN-1315936-C | Flame-resistant vinyl chloride based resin composition and formed product therefrom | MITSUBISHI PLASTICS INC (JP) | 2007-05-16 | — | — | CN | disclosed |
| US-20060014874-A1 | Flame-resistant vinyl chlorride based resin composition and formed product therefrom | MITSUBISHI PLASTICS, INC. (JP) | 2006-01-19 | — | — | US | disclosed |
| CN-1708550-A | Flame-resistant vinyl chloride based resin composition and formed product therefrom | MITSUBISHI PLASTICS INC (JP) | 2005-12-14 | — | — | CN | disclosed |
| CN-1054803-C | Polycarbonic acid ester resin layered products absorbing near-infrared and formed products made of same | DAICEL CHEM (JP) | 2000-07-26 | — | — | CN | disclosed |
| US-5514740-A | SHEET OR FILM HAVING CUPRIC SULFIDE DISPERSED THEREIN | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| US-5393443-A | Hard-coating, heat-absorbing composition and heat-shielding substance | JUJO PAPER CO., LTD. (JP) | 1995-02-28 | — | — | US | disclosed |
| CN-1094354-A | Polycarbonate-based resin laminate of absorption near infrared ray and formed body thereof | DAICEL CHEM (JP) | 1994-11-02 | — | — | CN | disclosed |
| US-4252963-A | CYCLIZATION OF PHENYLTHIOUREAS WITH THIONYL CHLORIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298340-A1 | Thiazol-Guanidine Derivatives Useful As A (Beta)-Related Pathologies | GRN, MAPT, GUCY1B1 | ALDH1A1 1302/4885TP53 1888/4885TYR 3166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.