Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | TYR | P14679 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725810 | 0.87 | ALDH1A1 (0.75) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL28294619 | 0.81 | TAS2R38 (0.60) | IDO1ALDH1A1TAS2R38CYP3A4CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL28802375 | 0.80 | IDO1 (0.57) | IDO1ALDH1A1TP53TYRTSHR | |
| SCHEMBL12071790 | 0.78 | ALDH1A1 (0.62) | IDO1ALDH1A1TP53TYRTSHR | |
| SCHEMBL728343 | 0.78 | ALDH1A1 (0.62) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL23752222 | 0.78 | IDO1 (0.59) | IDO1ALDH1A1TP53TYRTSHR | |
| SCHEMBL1822006 | 0.78 | ALDH1A1 (0.65) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL5435931 | 0.77 | IDO1 (1.00) | IDO1ALDH1A1KMT2ASMN1; SMN2GAA | |
| SCHEMBL1184889 | 0.76 | SIGMAR1 (0.53) | IDO1TP53CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11751583 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TP53TYRTSHRTAS2R38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113394456-A | Lithium metal battery electrolyte additive and application thereof | 厦门大学 | 2021-09-14 | — | — | CN | claimed |
| CN-107629022-B | Antibacterial synergist and preparation method and application thereof | 上海医药工业研究院 | 2024-11-12 | — | — | CN | disclosed |
| CN-118619952-A | Aloperine derivative, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-09-10 | — | — | CN | disclosed |
| CN-113394456-B | Lithium metal battery electrolyte additive and application thereof | 厦门大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-113394456-A | Lithium metal battery electrolyte additive and application thereof | 厦门大学 | 2021-09-14 | — | — | CN | disclosed |
| EP-3150705-B1 | METHOD FOR INDUCING MYOCARDIAL DIFFERENTIATION OF PLURIPOTENT STEM CELLS USING LOW-MOLECULAR COMPOUND | UNIV KYOTO (JP) | 2019-05-15 | — | — | EP | disclosed |
| EP-3150705-B1 | METHOD FOR INDUCING MYOCARDIAL DIFFERENTIATION OF PLURIPOTENT STEM CELLS USING LOW-MOLECULAR COMPOUND | UNIV KYOTO (JP) | 2019-05-15 | — | — | EP | disclosed |
| EP-2966166-B1 | PROMOTER OF DIFFERENTIATION OF PLURIPOTENT STEM CELL INTO MYOCARDIUM, WHICH COMPRISES EGF RECEPTOR INHIBITOR | UNIV KYOTO (JP) | 2019-04-03 | — | — | EP | disclosed |
| EP-2966166-B1 | PROMOTER OF DIFFERENTIATION OF PLURIPOTENT STEM CELL INTO MYOCARDIUM, WHICH COMPRISES EGF RECEPTOR INHIBITOR | UNIV KYOTO (JP) | 2019-04-03 | — | — | EP | disclosed |
| US-10233426-B2 | Method for inducing cardiac differentiation of pluripotent stem cell with low-molecular compounds | KYOTO UNIVERSITY (JP) | 2019-03-19 | — | — | US | disclosed |
| US-9499790-B2 | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells | KYOTO UNIVERSITY (JP) | 2016-11-22 | — | — | US | disclosed |
| US-9499790-B2 | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells | KYOTO UNIVERSITY (JP) | 2016-11-22 | — | — | US | disclosed |
| EP-3045451-A1 | COMPOUND PROMOTING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CARDIOMYOCYTES | Kyoto University (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-3045451-A1 | COMPOUND PROMOTING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CARDIOMYOCYTES | Kyoto University (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-2966166-A1 | PROMOTER OF DIFFERENTIATION OF PLURIPOTENT STEM CELL INTO MYOCARDIUM, WHICH COMPRISES EGF RECEPTOR INHIBITOR | Kyoto University (JP) | 2016-01-13 | — | — | EP | disclosed |
| US-20160002600-A1 | COMPOSITION FOR PROMOTING CARDIAC DIFFERENTIATION OF PLURIPOTENT STEM CELL COMPRISING EGFR INHIBITOR | KYOTO UNIVERSITY (JP) | 2016-01-07 | — | — | US | disclosed |
| US-20160002600-A1 | COMPOSITION FOR PROMOTING CARDIAC DIFFERENTIATION OF PLURIPOTENT STEM CELL COMPRISING EGFR INHIBITOR | KYOTO UNIVERSITY (JP) | 2016-01-07 | — | — | US | disclosed |
| US-20140127807-A1 | Method for Promoting Differentiation of Pluripotent Stem Cells into Cardiac Muscle Cells | KYOTO UNIVERSITY (JP) | 2014-05-08 | — | — | US | disclosed |
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | ARENA PHARMACEUTICALS, INC. | 2007-01-11 | — | — | US | disclosed |
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | TAISHO PHARMACEUTICAL CO., LTD. | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10233426-B2 | Method for inducing cardiac differentiation of pluripotent stem cell with low-molecular compounds | SRC, MYLK2, YES1 | IDO1 3748/4885ALDH1A1 2969/4885TP53 1153/4885 |
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | MCHR1, GPR119, MCHR2 | IDO1 210/4885ALDH1A1 2069/4885TP53 4773/4885 |
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | HCRTR2, MCHR1, MCHR2 | IDO1 289/4885ALDH1A1 2036/4885TP53 4482/4885 |
| US-20140127807-A1 | Method for Promoting Differentiation of Pluripotent Stem Cells into Cardiac Muscle Cells | TNNI3, MYLK2, TNNT2 | IDO1 4688/4885ALDH1A1 1072/4885TP53 3278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.