Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29460406 | 0.89 | MAOA (0.69) | MAOAMAOBKDM4ELMNAPOLB | |
| SCHEMBL22214975 | 0.89 | MAOA (0.69) | MAOAMAOBKDM4ELMNAPOLB | |
| SCHEMBL7285185 | 0.87 | POLB (0.53) | MAOAMAOBKDM4ELMNAPOLB | |
| SCHEMBL7284282 | 0.83 | KDM4E (0.50) | MAOAMAOBKDM4ELMNAPOLB | |
| SCHEMBL578947 | 0.81 | MAOB (0.75) | MAOAMAOBKDM4EALDH1A1MEN1 | |
| SCHEMBL8681578 | 0.81 | ALDH1A1 (0.61) | KDM4ELMNAPOLBKDM5AALDH1A1 | |
| SCHEMBL7284352 | 0.81 | KDM4E (0.53) | KDM4ELMNAPOLBKDM5AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27505257 | 0.80 | ALDH1A1 (0.59) | KDM4ELMNAPOLBKDM5AALDH1A1 | |
| SCHEMBL6633355 | 0.79 | ALDH1A1 (0.52) | MAOAMAOBKDM4ELMNAPOLB | |
| SCHEMBL7294269 | 0.79 | LMNA (0.54) | MAOAMAOBKDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760064-A | Cardiotonic agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0187322-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |