Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2743836 | 0.96 | LMNA (0.50) | LMNAKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL7284282 | 0.84 | KDM4E (0.50) | LMNAKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL5511473 | 0.84 | KDM4E (0.53) | LMNAKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL28068381 | 0.81 | ALDH1A1 (0.67) | LMNAKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL865350 | 0.81 | MAOA (0.58) | POLBMAPTMEN1KMT2AHDAC8 | |
| SCHEMBL7285185 | 0.80 | POLB (0.53) | LMNAKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL12035867 | 0.80 | PTPN1 (0.49) | LMNAPOLBMAPTCYP1A2CYP2C19 | |
| SCHEMBL7294266 | 0.80 | POLB (0.54) | LMNAKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL6633355 | 0.80 | ALDH1A1 (0.52) | LMNAKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL22214975 | 0.79 | MAOA (0.69) | LMNAKDM4EPOLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760064-A | Cardiotonic agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0187322-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |