Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24589110 | 0.87 | KDM4E (0.52) | POLBKDM4ELMNAMAPTTP53 | |
| SCHEMBL7284355 | 0.87 | MAOA (0.52) | POLBKDM4ELMNAMAPTTP53 | |
| SCHEMBL8681578 | 0.86 | ALDH1A1 (0.61) | POLBKDM4ELMNAMAPTTP53 | |
| SCHEMBL8625075 | 0.85 | ALDH1A1 (0.59) | POLBKDM4ELMNAMAPTTP53 | |
| SCHEMBL22214975 | 0.85 | MAOA (0.69) | POLBKDM4ELMNAALDH1A1MAPK1 | |
| SCHEMBL29460406 | 0.85 | MAOA (0.69) | POLBKDM4ELMNAALDH1A1MAPK1 | |
| SCHEMBL8013977 | 0.84 | ALOX15 (0.61) | POLBKDM4ELMNAMAPTTP53 | |
| SCHEMBL8011529 | 0.84 | LMNA (0.62) | POLBKDM4ELMNAMAPTTP53 | |
| Hydrochloric Acid SCHEMBL27505257 | 0.84 | ALDH1A1 (0.59) | POLBKDM4ELMNAMAPTTP53 | |
| SCHEMBL5288304 | 0.83 | MAPT (0.59) | POLBKDM4ELMNAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760064-A | Cardiotonic agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0187322-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |