Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280821 | 0.95 | ALDH1A1 (0.47) | ALDH1A1HPGDRAB9ASMN1; SMN2SIGMAR1 | |
| SCHEMBL7275560 | 0.93 | ALDH1A1 (0.45) | ALDH1A1HPGDP2RX7RAB9ASMN1; SMN2 | |
| SCHEMBL7275596 | 0.88 | DRD2 (0.41) | HDAC2 | |
| SCHEMBL7273369 | 0.86 | MAOA (0.38) | RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL7275887 | 0.85 | F10 (0.49) | PLG | |
| Hydrochloric Acid SCHEMBL7272455 | 0.84 | F10 (0.45) | PLG | |
| SCHEMBL7274708 | 0.83 | CHRM4 (0.42) | HPGDRAB9ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL7279790 | 0.83 | F10 (0.42) | — | |
| SCHEMBL7273655 | 0.83 | SIGMAR1 (0.40) | ALDH1A1HPGDRAB9ASMN1; SMN2SIGMAR1 | |
| SCHEMBL7278834 | 0.83 | HTR1A (0.39) | HPGDRAB9APLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |