Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 3/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.42 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496581 | 0.80 | GRM2 (0.49) | CYP1A2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14486238 | 0.80 | GRM2 (0.49) | CYP1A2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10447315 | 0.79 | CYP1A2 (0.55) | CYP1A2PRKCAPRKCDSLC6A2SLC6A4 | |
| SCHEMBL7628613 | 0.78 | SIGMAR1 (0.56) | — | |
| SCHEMBL20395688 | 0.77 | CYP1A2 (0.42) | CYP1A2 | |
| SCHEMBL10736619 | 0.77 | PRKCA (0.49) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL10736607 | 0.77 | PRKCA (0.49) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL18227495 | 0.77 | LMNA (0.46) | CYP1A2MEN1KMT2ATAAR1 | |
| SCHEMBL10736601 | 0.77 | PRKCA (0.49) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL18227496 | 0.77 | LMNA (0.46) | CYP1A2MEN1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277588-B1 | PROLINAL DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |
| US-5091406-A | Cognition activators | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
| US-4977180-A | ANTIAMNESIA AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-12-11 | — | — | US | disclosed |
| EP-0277588-A1 | Prolinal derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-08-10 | — | — | EP | disclosed |