Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758577 | 0.77 | TSHR (0.36) | ADRA1A | |
| SCHEMBL9101372 | 0.76 | TSHR (0.37) | DRD2ADRA1A | |
| SCHEMBL4757355 | 0.70 | PYGM (0.39) | — | |
| SCHEMBL11210015 | 0.70 | CACNA2D1 (0.46) | OPRM1CHRM2CHRM1DRD2ADRA1A | |
| SCHEMBL10847722 | 0.66 | CYP2C9 (0.59) | OPRM1HTR1ACHRM1DRD2ADRA1D | |
| SCHEMBL12123733 | 0.66 | PRCP (0.55) | BACE1CCR5PRCPCHRM2HTR1A | |
| SCHEMBL4758583 | 0.66 | PYGL (0.38) | HTR1AADRA1A | |
| SCHEMBL14282941 | 0.65 | PRCP (0.54) | BACE1PRCPCARM1PRMT6 | |
| SCHEMBL2365028 | 0.65 | TSHR (0.37) | ADRA1A | |
| SCHEMBL4695183 | 0.65 | PRCP (0.52) | BACE1CCR5PRCPCHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138505-A2 | Dihydropyridine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-04-24 | — | — | EP | disclosed |