Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295865 | 0.84 | ROCK2 (0.60) | SMYD3LMNAGAAALDH1A1KMT2A | |
| SCHEMBL7294386 | 0.80 | SMYD3 (0.55) | SMYD3USP2TP53LMNATRPV1 | |
| SCHEMBL7287369 | 0.79 | TP53 (0.51) | SMYD3TP53LMNATRPV1GAA | |
| SCHEMBL7297231 | 0.76 | SMYD3 (0.61) | SMYD3TP53LMNAGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL7309309 | 0.75 | KDM1A (0.42) | KDM1AMEN1KMT2A | |
| SCHEMBL7294948 | 0.74 | PRKAB2 (0.56) | TP53 | |
| SCHEMBL10365448 | 0.70 | MAP4K1 (0.65) | TP53TRPV1GAASMN1; SMN2HDAC3 | |
| SCHEMBL14619598 | 0.69 | MCHR1 (0.53) | CARM1PRMT6 | |
| SCHEMBL14619828 | 0.68 | MCHR1 (0.52) | ALDH1A1 | |
| SCHEMBL7374128 | 0.68 | LMNA (0.58) | LMNAGAAKDM1AKMT2AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255134-A2 | Carbostyril derivatives and salts thereof, process for preparing them, and cardiotonic composition containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-03 | — | — | EP | disclosed |